Treatment time and circadian genotype interact to influence radiotherapy side-effects. A prospective European validation study using the REQUITE cohort

BACKGROUND: Circadian rhythm impacts broad biological processes, including response to cancer treatment. Evidence conflicts on whether treatment time affects risk of radiotherapy side-effects, likely because of differing time analyses and target tissues. We previously showed interactive effects of t...

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Detalles Bibliográficos
Autores principales: Webb, Adam J., Harper, Emily, Rattay, Tim, Aguado-Barrera, Miguel E., Azria, David, Bourgier, Celine, Brengues, Muriel, Briers, Erik, Bultijnck, Renée, Chang-Claude, Jenny, Choudhury, Ananya, Cicchetti, Alessandro, De Ruysscher, Dirk, De Santis, Maria Carmen, Dunning, Alison M., Elliott, Rebecca M., Fachal, Laura, Gómez-Caamaño, Antonio, Gutiérrez-Enríquez, Sara, Johnson, Kerstie, Lobato-Busto, Ramón, Kerns, Sarah L., Post, Giselle, Rancati, Tiziana, Reyes, Victoria, Rosenstein, Barry S., Seibold, Petra, Seoane, Alejandro, Sosa-Fajardo, Paloma, Sperk, Elena, Taboada-Valladares, Begoña, Valdagni, Riccardo, Vega, Ana, Veldeman, Liv, Ward, Tim, West, Catharine M., Symonds, R. Paul, Talbot, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486558/
https://www.ncbi.nlm.nih.gov/pubmed/36130474
http://dx.doi.org/10.1016/j.ebiom.2022.104269

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