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Design centering enables robustness screening of pattern formation models
MOTIVATION: Access to unprecedented amounts of quantitative biological data allows us to build and test biochemically accurate reaction–diffusion models of intracellular processes. However, any increase in model complexity increases the number of unknown parameters and, thus, the computational cost...
Autores principales: | Solomatina, Anastasia, Cezanne, Alice, Kalaidzidis, Yannis, Zerial, Marino, Sbalzarini, Ivo F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486588/ https://www.ncbi.nlm.nih.gov/pubmed/36124805 http://dx.doi.org/10.1093/bioinformatics/btac480 |
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