Cargando…

Steroid induced psychosis in a child with nephrotic syndrome: A case report

BACKGROUND: and Importance: Steroids induced psychosis is one of major adverse effects of corticosteroids therapy especially in patients with disease causing low serum albumin level like nephrotic syndrome. The literature review about this adverse effects is lesser in children than adults population...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhusal, Amrit, Bhandari, Silan, Pokhrel, Sagar, Yadav, Shankar Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486695/
https://www.ncbi.nlm.nih.gov/pubmed/36147063
http://dx.doi.org/10.1016/j.amsu.2022.104515
_version_ 1784792333617725440
author Bhusal, Amrit
Bhandari, Silan
Pokhrel, Sagar
Yadav, Shankar Prasad
author_facet Bhusal, Amrit
Bhandari, Silan
Pokhrel, Sagar
Yadav, Shankar Prasad
author_sort Bhusal, Amrit
collection PubMed
description BACKGROUND: and Importance: Steroids induced psychosis is one of major adverse effects of corticosteroids therapy especially in patients with disease causing low serum albumin level like nephrotic syndrome. The literature review about this adverse effects is lesser in children than adults population. The management is done by tapering dose of steroids in aid of immunosuppressive drug with an antipsychotics drug. CASE PRESENTATION: Here we present a case of 14 years old female child known case of nephrotic syndrome secondary to Focal segmental glomerulosclerosis with steroids induced psychosis who is managed by tapering dose of prednisolone with Tacrolimus as immunosuppressive and Quetiapine as antipsychotic. CONCLUSION: The prevalence of steroids induced psychosis is higher in our locality which is still unreported due to lack of detailed history and proper diagnosis and it is manageable if early diagnosis and treatment is initiated. Thus, proper counselling to parents about the adverse effect of steroids therapy and timely follow up will prevent Nepalese children from this illness.
format Online
Article
Text
id pubmed-9486695
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-94866952022-09-21 Steroid induced psychosis in a child with nephrotic syndrome: A case report Bhusal, Amrit Bhandari, Silan Pokhrel, Sagar Yadav, Shankar Prasad Ann Med Surg (Lond) Case Report BACKGROUND: and Importance: Steroids induced psychosis is one of major adverse effects of corticosteroids therapy especially in patients with disease causing low serum albumin level like nephrotic syndrome. The literature review about this adverse effects is lesser in children than adults population. The management is done by tapering dose of steroids in aid of immunosuppressive drug with an antipsychotics drug. CASE PRESENTATION: Here we present a case of 14 years old female child known case of nephrotic syndrome secondary to Focal segmental glomerulosclerosis with steroids induced psychosis who is managed by tapering dose of prednisolone with Tacrolimus as immunosuppressive and Quetiapine as antipsychotic. CONCLUSION: The prevalence of steroids induced psychosis is higher in our locality which is still unreported due to lack of detailed history and proper diagnosis and it is manageable if early diagnosis and treatment is initiated. Thus, proper counselling to parents about the adverse effect of steroids therapy and timely follow up will prevent Nepalese children from this illness. Elsevier 2022-08-24 /pmc/articles/PMC9486695/ /pubmed/36147063 http://dx.doi.org/10.1016/j.amsu.2022.104515 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Bhusal, Amrit
Bhandari, Silan
Pokhrel, Sagar
Yadav, Shankar Prasad
Steroid induced psychosis in a child with nephrotic syndrome: A case report
title Steroid induced psychosis in a child with nephrotic syndrome: A case report
title_full Steroid induced psychosis in a child with nephrotic syndrome: A case report
title_fullStr Steroid induced psychosis in a child with nephrotic syndrome: A case report
title_full_unstemmed Steroid induced psychosis in a child with nephrotic syndrome: A case report
title_short Steroid induced psychosis in a child with nephrotic syndrome: A case report
title_sort steroid induced psychosis in a child with nephrotic syndrome: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486695/
https://www.ncbi.nlm.nih.gov/pubmed/36147063
http://dx.doi.org/10.1016/j.amsu.2022.104515
work_keys_str_mv AT bhusalamrit steroidinducedpsychosisinachildwithnephroticsyndromeacasereport
AT bhandarisilan steroidinducedpsychosisinachildwithnephroticsyndromeacasereport
AT pokhrelsagar steroidinducedpsychosisinachildwithnephroticsyndromeacasereport
AT yadavshankarprasad steroidinducedpsychosisinachildwithnephroticsyndromeacasereport