Non-Hodgkin's lymphoma masquerading as splenic abscess: A case report

BACKGROUND: Non-Hodgkin's lymphoma (NHL) is a monoclonal proliferation of lymphoid cells from B lineage. Although NHLs are primarily hematological tumors of lymph nodes but rarely can involve extranodal sites such as the spleen. CASE REPORT: A 29-year-old female patient presented with low-grade...

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Detalles Bibliográficos
Autores principales: Khan, Qaisar Ali, Mumtaz, Arif, Baqi, Abdul, Ain, Hoor Ul, Mahfooz, Rabia Salman, Asim, Nowshad, Iram, Sumaira, Hussien Mohamed Ahmed, Khabab Abbasher, Tahir, Muhammad Junaid, Yousaf, Zohaib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486706/
https://www.ncbi.nlm.nih.gov/pubmed/36147111
http://dx.doi.org/10.1016/j.amsu.2022.104449
Descripción
Sumario:BACKGROUND: Non-Hodgkin's lymphoma (NHL) is a monoclonal proliferation of lymphoid cells from B lineage. Although NHLs are primarily hematological tumors of lymph nodes but rarely can involve extranodal sites such as the spleen. CASE REPORT: A 29-year-old female patient presented with low-grade fever, cough, anemia, weight loss, tender left hypochondrium, and splenomegaly. A hypodense lesion in the spleen with central necrosis, having strong positivity for common leukocyte antigen (LCA), CD 20, and CD 10, led to a diffuse large B cell lymphoma diagnosis. The patient had an excellent clinical post-splenectomy response to combination chemotherapy and immunotherapy. CONCLUSION: NHL can present with symptomatic extra-nodal involvement without enlarged lymph nodes.

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