Non-Hodgkin's lymphoma masquerading as splenic abscess: A case report

BACKGROUND: Non-Hodgkin's lymphoma (NHL) is a monoclonal proliferation of lymphoid cells from B lineage. Although NHLs are primarily hematological tumors of lymph nodes but rarely can involve extranodal sites such as the spleen. CASE REPORT: A 29-year-old female patient presented with low-grade...

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Autores principales: Khan, Qaisar Ali, Mumtaz, Arif, Baqi, Abdul, Ain, Hoor Ul, Mahfooz, Rabia Salman, Asim, Nowshad, Iram, Sumaira, Hussien Mohamed Ahmed, Khabab Abbasher, Tahir, Muhammad Junaid, Yousaf, Zohaib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486706/
https://www.ncbi.nlm.nih.gov/pubmed/36147111
http://dx.doi.org/10.1016/j.amsu.2022.104449
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author Khan, Qaisar Ali
Mumtaz, Arif
Baqi, Abdul
Ain, Hoor Ul
Mahfooz, Rabia Salman
Asim, Nowshad
Iram, Sumaira
Hussien Mohamed Ahmed, Khabab Abbasher
Tahir, Muhammad Junaid
Yousaf, Zohaib
author_facet Khan, Qaisar Ali
Mumtaz, Arif
Baqi, Abdul
Ain, Hoor Ul
Mahfooz, Rabia Salman
Asim, Nowshad
Iram, Sumaira
Hussien Mohamed Ahmed, Khabab Abbasher
Tahir, Muhammad Junaid
Yousaf, Zohaib
author_sort Khan, Qaisar Ali
collection PubMed
description BACKGROUND: Non-Hodgkin's lymphoma (NHL) is a monoclonal proliferation of lymphoid cells from B lineage. Although NHLs are primarily hematological tumors of lymph nodes but rarely can involve extranodal sites such as the spleen. CASE REPORT: A 29-year-old female patient presented with low-grade fever, cough, anemia, weight loss, tender left hypochondrium, and splenomegaly. A hypodense lesion in the spleen with central necrosis, having strong positivity for common leukocyte antigen (LCA), CD 20, and CD 10, led to a diffuse large B cell lymphoma diagnosis. The patient had an excellent clinical post-splenectomy response to combination chemotherapy and immunotherapy. CONCLUSION: NHL can present with symptomatic extra-nodal involvement without enlarged lymph nodes.
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spelling pubmed-94867062022-09-21 Non-Hodgkin's lymphoma masquerading as splenic abscess: A case report Khan, Qaisar Ali Mumtaz, Arif Baqi, Abdul Ain, Hoor Ul Mahfooz, Rabia Salman Asim, Nowshad Iram, Sumaira Hussien Mohamed Ahmed, Khabab Abbasher Tahir, Muhammad Junaid Yousaf, Zohaib Ann Med Surg (Lond) Case Report BACKGROUND: Non-Hodgkin's lymphoma (NHL) is a monoclonal proliferation of lymphoid cells from B lineage. Although NHLs are primarily hematological tumors of lymph nodes but rarely can involve extranodal sites such as the spleen. CASE REPORT: A 29-year-old female patient presented with low-grade fever, cough, anemia, weight loss, tender left hypochondrium, and splenomegaly. A hypodense lesion in the spleen with central necrosis, having strong positivity for common leukocyte antigen (LCA), CD 20, and CD 10, led to a diffuse large B cell lymphoma diagnosis. The patient had an excellent clinical post-splenectomy response to combination chemotherapy and immunotherapy. CONCLUSION: NHL can present with symptomatic extra-nodal involvement without enlarged lymph nodes. Elsevier 2022-08-18 /pmc/articles/PMC9486706/ /pubmed/36147111 http://dx.doi.org/10.1016/j.amsu.2022.104449 Text en © 2022 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Khan, Qaisar Ali
Mumtaz, Arif
Baqi, Abdul
Ain, Hoor Ul
Mahfooz, Rabia Salman
Asim, Nowshad
Iram, Sumaira
Hussien Mohamed Ahmed, Khabab Abbasher
Tahir, Muhammad Junaid
Yousaf, Zohaib
Non-Hodgkin's lymphoma masquerading as splenic abscess: A case report
title Non-Hodgkin's lymphoma masquerading as splenic abscess: A case report
title_full Non-Hodgkin's lymphoma masquerading as splenic abscess: A case report
title_fullStr Non-Hodgkin's lymphoma masquerading as splenic abscess: A case report
title_full_unstemmed Non-Hodgkin's lymphoma masquerading as splenic abscess: A case report
title_short Non-Hodgkin's lymphoma masquerading as splenic abscess: A case report
title_sort non-hodgkin's lymphoma masquerading as splenic abscess: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486706/
https://www.ncbi.nlm.nih.gov/pubmed/36147111
http://dx.doi.org/10.1016/j.amsu.2022.104449
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