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Two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: A case report

INTRODUCTION AND IMPORTANCE: Lupus nephritis is particularly a very concerning occurrence due to the susceptibility for potential renal damage and ultimately renal failure. Cardiac involvement was present as well in the form of pericarditis. Our study reports a case of lupus nephritis that has had a...

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Detalles Bibliográficos
Autores principales: AlGhobaishi, Abdullah, Mousa, Ahmed Hafez, Alshaltoni, Reham Salama, Mohsen, Amani Sail, Baothman, Abdullah, Adem, Hanan, Eisa, Yasir, Amin, Abeer, Edrees, Burhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486710/
https://www.ncbi.nlm.nih.gov/pubmed/36147129
http://dx.doi.org/10.1016/j.amsu.2022.104541
Descripción
Sumario:INTRODUCTION AND IMPORTANCE: Lupus nephritis is particularly a very concerning occurrence due to the susceptibility for potential renal damage and ultimately renal failure. Cardiac involvement was present as well in the form of pericarditis. Our study reports a case of lupus nephritis that has had a very severe course of fluctuations between relapses and improvements which constantly necessitated an MDT interference at various points. CASE PRESENTATION: We report a case of a 13-year-old female patient who presented with a 5-day history of fever, dizziness, joint pain, menorrhagia, convulsions, and visual disturbances. Essential diagnostic tests took place and a diagnosis of lupus nephritis was confirmed. CONCLUSION: In conclusion we found that a combination of various treatment modalities and flexibility in decision making in response to changes in the clinical course are vital to treatment success. Utilization of plasma exchange which resulted in an enormous drop in the percentage of fragmented red blood cells (RBCs) from 9.8% to 1.8%.