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Two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: A case report
INTRODUCTION AND IMPORTANCE: Lupus nephritis is particularly a very concerning occurrence due to the susceptibility for potential renal damage and ultimately renal failure. Cardiac involvement was present as well in the form of pericarditis. Our study reports a case of lupus nephritis that has had a...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486710/ https://www.ncbi.nlm.nih.gov/pubmed/36147129 http://dx.doi.org/10.1016/j.amsu.2022.104541 |
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author | AlGhobaishi, Abdullah Mousa, Ahmed Hafez Alshaltoni, Reham Salama Mohsen, Amani Sail Baothman, Abdullah Adem, Hanan Eisa, Yasir Amin, Abeer Edrees, Burhan |
author_facet | AlGhobaishi, Abdullah Mousa, Ahmed Hafez Alshaltoni, Reham Salama Mohsen, Amani Sail Baothman, Abdullah Adem, Hanan Eisa, Yasir Amin, Abeer Edrees, Burhan |
author_sort | AlGhobaishi, Abdullah |
collection | PubMed |
description | INTRODUCTION AND IMPORTANCE: Lupus nephritis is particularly a very concerning occurrence due to the susceptibility for potential renal damage and ultimately renal failure. Cardiac involvement was present as well in the form of pericarditis. Our study reports a case of lupus nephritis that has had a very severe course of fluctuations between relapses and improvements which constantly necessitated an MDT interference at various points. CASE PRESENTATION: We report a case of a 13-year-old female patient who presented with a 5-day history of fever, dizziness, joint pain, menorrhagia, convulsions, and visual disturbances. Essential diagnostic tests took place and a diagnosis of lupus nephritis was confirmed. CONCLUSION: In conclusion we found that a combination of various treatment modalities and flexibility in decision making in response to changes in the clinical course are vital to treatment success. Utilization of plasma exchange which resulted in an enormous drop in the percentage of fragmented red blood cells (RBCs) from 9.8% to 1.8%. |
format | Online Article Text |
id | pubmed-9486710 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-94867102022-09-21 Two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: A case report AlGhobaishi, Abdullah Mousa, Ahmed Hafez Alshaltoni, Reham Salama Mohsen, Amani Sail Baothman, Abdullah Adem, Hanan Eisa, Yasir Amin, Abeer Edrees, Burhan Ann Med Surg (Lond) Case Report INTRODUCTION AND IMPORTANCE: Lupus nephritis is particularly a very concerning occurrence due to the susceptibility for potential renal damage and ultimately renal failure. Cardiac involvement was present as well in the form of pericarditis. Our study reports a case of lupus nephritis that has had a very severe course of fluctuations between relapses and improvements which constantly necessitated an MDT interference at various points. CASE PRESENTATION: We report a case of a 13-year-old female patient who presented with a 5-day history of fever, dizziness, joint pain, menorrhagia, convulsions, and visual disturbances. Essential diagnostic tests took place and a diagnosis of lupus nephritis was confirmed. CONCLUSION: In conclusion we found that a combination of various treatment modalities and flexibility in decision making in response to changes in the clinical course are vital to treatment success. Utilization of plasma exchange which resulted in an enormous drop in the percentage of fragmented red blood cells (RBCs) from 9.8% to 1.8%. Elsevier 2022-09-01 /pmc/articles/PMC9486710/ /pubmed/36147129 http://dx.doi.org/10.1016/j.amsu.2022.104541 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report AlGhobaishi, Abdullah Mousa, Ahmed Hafez Alshaltoni, Reham Salama Mohsen, Amani Sail Baothman, Abdullah Adem, Hanan Eisa, Yasir Amin, Abeer Edrees, Burhan Two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: A case report |
title | Two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: A case report |
title_full | Two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: A case report |
title_fullStr | Two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: A case report |
title_full_unstemmed | Two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: A case report |
title_short | Two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: A case report |
title_sort | two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486710/ https://www.ncbi.nlm.nih.gov/pubmed/36147129 http://dx.doi.org/10.1016/j.amsu.2022.104541 |
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