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Two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: A case report

INTRODUCTION AND IMPORTANCE: Lupus nephritis is particularly a very concerning occurrence due to the susceptibility for potential renal damage and ultimately renal failure. Cardiac involvement was present as well in the form of pericarditis. Our study reports a case of lupus nephritis that has had a...

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Autores principales: AlGhobaishi, Abdullah, Mousa, Ahmed Hafez, Alshaltoni, Reham Salama, Mohsen, Amani Sail, Baothman, Abdullah, Adem, Hanan, Eisa, Yasir, Amin, Abeer, Edrees, Burhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486710/
https://www.ncbi.nlm.nih.gov/pubmed/36147129
http://dx.doi.org/10.1016/j.amsu.2022.104541
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author AlGhobaishi, Abdullah
Mousa, Ahmed Hafez
Alshaltoni, Reham Salama
Mohsen, Amani Sail
Baothman, Abdullah
Adem, Hanan
Eisa, Yasir
Amin, Abeer
Edrees, Burhan
author_facet AlGhobaishi, Abdullah
Mousa, Ahmed Hafez
Alshaltoni, Reham Salama
Mohsen, Amani Sail
Baothman, Abdullah
Adem, Hanan
Eisa, Yasir
Amin, Abeer
Edrees, Burhan
author_sort AlGhobaishi, Abdullah
collection PubMed
description INTRODUCTION AND IMPORTANCE: Lupus nephritis is particularly a very concerning occurrence due to the susceptibility for potential renal damage and ultimately renal failure. Cardiac involvement was present as well in the form of pericarditis. Our study reports a case of lupus nephritis that has had a very severe course of fluctuations between relapses and improvements which constantly necessitated an MDT interference at various points. CASE PRESENTATION: We report a case of a 13-year-old female patient who presented with a 5-day history of fever, dizziness, joint pain, menorrhagia, convulsions, and visual disturbances. Essential diagnostic tests took place and a diagnosis of lupus nephritis was confirmed. CONCLUSION: In conclusion we found that a combination of various treatment modalities and flexibility in decision making in response to changes in the clinical course are vital to treatment success. Utilization of plasma exchange which resulted in an enormous drop in the percentage of fragmented red blood cells (RBCs) from 9.8% to 1.8%.
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spelling pubmed-94867102022-09-21 Two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: A case report AlGhobaishi, Abdullah Mousa, Ahmed Hafez Alshaltoni, Reham Salama Mohsen, Amani Sail Baothman, Abdullah Adem, Hanan Eisa, Yasir Amin, Abeer Edrees, Burhan Ann Med Surg (Lond) Case Report INTRODUCTION AND IMPORTANCE: Lupus nephritis is particularly a very concerning occurrence due to the susceptibility for potential renal damage and ultimately renal failure. Cardiac involvement was present as well in the form of pericarditis. Our study reports a case of lupus nephritis that has had a very severe course of fluctuations between relapses and improvements which constantly necessitated an MDT interference at various points. CASE PRESENTATION: We report a case of a 13-year-old female patient who presented with a 5-day history of fever, dizziness, joint pain, menorrhagia, convulsions, and visual disturbances. Essential diagnostic tests took place and a diagnosis of lupus nephritis was confirmed. CONCLUSION: In conclusion we found that a combination of various treatment modalities and flexibility in decision making in response to changes in the clinical course are vital to treatment success. Utilization of plasma exchange which resulted in an enormous drop in the percentage of fragmented red blood cells (RBCs) from 9.8% to 1.8%. Elsevier 2022-09-01 /pmc/articles/PMC9486710/ /pubmed/36147129 http://dx.doi.org/10.1016/j.amsu.2022.104541 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
AlGhobaishi, Abdullah
Mousa, Ahmed Hafez
Alshaltoni, Reham Salama
Mohsen, Amani Sail
Baothman, Abdullah
Adem, Hanan
Eisa, Yasir
Amin, Abeer
Edrees, Burhan
Two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: A case report
title Two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: A case report
title_full Two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: A case report
title_fullStr Two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: A case report
title_full_unstemmed Two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: A case report
title_short Two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: A case report
title_sort two concomitant thrombotic microangiopathies in the background of systemic lupus erythematosus: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486710/
https://www.ncbi.nlm.nih.gov/pubmed/36147129
http://dx.doi.org/10.1016/j.amsu.2022.104541
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