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DNA methylation as a pharmacodynamic marker of glucocorticoid response and glioma survival

Assessing individual responses to glucocorticoid drug therapies that compromise immune status and affect survival outcomes in neuro-oncology is a great challenge. Here we introduce a blood-based neutrophil dexamethasone methylation index (NDMI) that provides a measure of the epigenetic response of s...

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Detalles Bibliográficos
Autores principales:	Wiencke, J. K., Molinaro, Annette M., Warrier, Gayathri, Rice, Terri, Clarke, Jennifer, Taylor, Jennie W., Wrensch, Margaret, Hansen, Helen, McCoy, Lucie, Tang, Emily, Tamaki, Stan J., Tamaki, Courtney M., Nissen, Emily, Bracci, Paige, Salas, Lucas A., Koestler, Devin C., Christensen, Brock C., Zhang, Ze, Kelsey, Karl T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486797/ https://www.ncbi.nlm.nih.gov/pubmed/36127421 http://dx.doi.org/10.1038/s41467-022-33215-x

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