Shaping Neonatal Immunization by Tuning the Delivery of Synergistic Adjuvants via Nanocarriers

[Image: see text] Adjuvanted nanocarrier-based vaccines hold substantial potential for applications in novel early-life immunization strategies. Here, via mouse and human age-specific in vitro modeling, we identified the combination of a small-molecule STING agonist (2′3′-cyclic GMP-AMP, cGAMP) and...

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Detalles Bibliográficos
Autores principales: Barman, Soumik, Borriello, Francesco, Brook, Byron, Pietrasanta, Carlo, De Leon, Maria, Sweitzer, Cali, Menon, Manisha, van Haren, Simon D., Soni, Dheeraj, Saito, Yoshine, Nanishi, Etsuro, Yi, Sijia, Bobbala, Sharan, Levy, Ofer, Scott, Evan A., Dowling, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486804/
https://www.ncbi.nlm.nih.gov/pubmed/36028220
http://dx.doi.org/10.1021/acschembio.2c00497

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