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Bizarre wide complex tachycardia caused by sodium channel toxicity secondary to the management of status epilepticus: Case report

INTRODUCTION AND IMPORTANCE: Antiepileptic drugs therapy are associated with myriad adverse effects. Some of antiepileptic drugs (AEDs) inhibit sodium channels that may cause dysrhythmia and hemodynamic instability if administered in too high dose. CASE PRESENTATION: We describe a patient with wide...

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Autor principal: AlMutairi, Ghazi T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486842/
https://www.ncbi.nlm.nih.gov/pubmed/36147138
http://dx.doi.org/10.1016/j.amsu.2022.104558
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author AlMutairi, Ghazi T.
author_facet AlMutairi, Ghazi T.
author_sort AlMutairi, Ghazi T.
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description INTRODUCTION AND IMPORTANCE: Antiepileptic drugs therapy are associated with myriad adverse effects. Some of antiepileptic drugs (AEDs) inhibit sodium channels that may cause dysrhythmia and hemodynamic instability if administered in too high dose. CASE PRESENTATION: We describe a patient with wide complex tachycardia likely secondary to medical management of status epilepticus specifically secondary to sodium channels blockade that successfully managed with supportive care and one session of hemodialysis. CONCLUSION: In this case report, we discuss the successful management of the first reported combination of AEDs (Phenytoin and lacosamide) toxicity using supportive care and extracorporeal removal.
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spelling pubmed-94868422022-09-21 Bizarre wide complex tachycardia caused by sodium channel toxicity secondary to the management of status epilepticus: Case report AlMutairi, Ghazi T. Ann Med Surg (Lond) Case Report INTRODUCTION AND IMPORTANCE: Antiepileptic drugs therapy are associated with myriad adverse effects. Some of antiepileptic drugs (AEDs) inhibit sodium channels that may cause dysrhythmia and hemodynamic instability if administered in too high dose. CASE PRESENTATION: We describe a patient with wide complex tachycardia likely secondary to medical management of status epilepticus specifically secondary to sodium channels blockade that successfully managed with supportive care and one session of hemodialysis. CONCLUSION: In this case report, we discuss the successful management of the first reported combination of AEDs (Phenytoin and lacosamide) toxicity using supportive care and extracorporeal removal. Elsevier 2022-09-02 /pmc/articles/PMC9486842/ /pubmed/36147138 http://dx.doi.org/10.1016/j.amsu.2022.104558 Text en © 2022 The Author https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
AlMutairi, Ghazi T.
Bizarre wide complex tachycardia caused by sodium channel toxicity secondary to the management of status epilepticus: Case report
title Bizarre wide complex tachycardia caused by sodium channel toxicity secondary to the management of status epilepticus: Case report
title_full Bizarre wide complex tachycardia caused by sodium channel toxicity secondary to the management of status epilepticus: Case report
title_fullStr Bizarre wide complex tachycardia caused by sodium channel toxicity secondary to the management of status epilepticus: Case report
title_full_unstemmed Bizarre wide complex tachycardia caused by sodium channel toxicity secondary to the management of status epilepticus: Case report
title_short Bizarre wide complex tachycardia caused by sodium channel toxicity secondary to the management of status epilepticus: Case report
title_sort bizarre wide complex tachycardia caused by sodium channel toxicity secondary to the management of status epilepticus: case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486842/
https://www.ncbi.nlm.nih.gov/pubmed/36147138
http://dx.doi.org/10.1016/j.amsu.2022.104558
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