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Short term recurrence and survival rate of breast cancer patients post surgical treatment; north borneo experience
INTRODUCTION: Breast cancer is the most common cancer among women and one of the major causes of mortality and morbidity worldwide. The aim of this study is to determine two-year cumulative recurrence rates and survival rates and their influential factors among women with breast cancer after surgica...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486850/ https://www.ncbi.nlm.nih.gov/pubmed/36147066 http://dx.doi.org/10.1016/j.amsu.2022.104560 |
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author | Kumilau, Raynee Hayati, Firdaus Liew, Jerry ES. Sharif, Siti Zubaidah Sahid Nik Lah, Nik Amin |
author_facet | Kumilau, Raynee Hayati, Firdaus Liew, Jerry ES. Sharif, Siti Zubaidah Sahid Nik Lah, Nik Amin |
author_sort | Kumilau, Raynee |
collection | PubMed |
description | INTRODUCTION: Breast cancer is the most common cancer among women and one of the major causes of mortality and morbidity worldwide. The aim of this study is to determine two-year cumulative recurrence rates and survival rates and their influential factors among women with breast cancer after surgical treatment. METHODS: The breast cancer registry with focus on patient's outcome after treatment was retrospectively review for relevant data. The study was started on 2019. All breast cancer patients who underwent surgical procedure between 2016 and 2019 were identified and recruited in this study and was follow up for two year. We performed Kaplan Meier method to determine 2-year recurrence rates and survival rates and compared unadjusted survival statistics using Log-rank test between baseline variables and outcomes. RESULT: From 2016 to 2019, a total of 482 breast cancer patients underwent surgical procedure. The overall observed 2-year recurrence rate among breast cancer patients after surgical treatment was 11.8% (95%CI:8.5,16.4) while for the survival rate was 94.8% (95% CI:91.8,96.7). Log rank test showed that lymph node involvement (p < 0.001) and high lymph node ratio (p < 0.001) were associated with higher cumulative recurrence rates. Meanwhile, stage 4 breast cancer (p = 0.001), higher grade tumour (p = 0.011), larger tumour size (>5 cm) (P = 0.005) and type of tumour (p = 0.018) were demonstrated to have lower survival rates. CONCLUSION: Recurrence rate were significant predictor among patient with lymph node involvement and higher lymph node ratio, while stages of tumour, tumour grade, size of tumour and type of tumour were all highly significant predictor for survival rate. Therefore, the aim for early diagnosis and management of breast cancer is crucial in improving the treatment outcome. |
format | Online Article Text |
id | pubmed-9486850 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-94868502022-09-21 Short term recurrence and survival rate of breast cancer patients post surgical treatment; north borneo experience Kumilau, Raynee Hayati, Firdaus Liew, Jerry ES. Sharif, Siti Zubaidah Sahid Nik Lah, Nik Amin Ann Med Surg (Lond) Cohort Study INTRODUCTION: Breast cancer is the most common cancer among women and one of the major causes of mortality and morbidity worldwide. The aim of this study is to determine two-year cumulative recurrence rates and survival rates and their influential factors among women with breast cancer after surgical treatment. METHODS: The breast cancer registry with focus on patient's outcome after treatment was retrospectively review for relevant data. The study was started on 2019. All breast cancer patients who underwent surgical procedure between 2016 and 2019 were identified and recruited in this study and was follow up for two year. We performed Kaplan Meier method to determine 2-year recurrence rates and survival rates and compared unadjusted survival statistics using Log-rank test between baseline variables and outcomes. RESULT: From 2016 to 2019, a total of 482 breast cancer patients underwent surgical procedure. The overall observed 2-year recurrence rate among breast cancer patients after surgical treatment was 11.8% (95%CI:8.5,16.4) while for the survival rate was 94.8% (95% CI:91.8,96.7). Log rank test showed that lymph node involvement (p < 0.001) and high lymph node ratio (p < 0.001) were associated with higher cumulative recurrence rates. Meanwhile, stage 4 breast cancer (p = 0.001), higher grade tumour (p = 0.011), larger tumour size (>5 cm) (P = 0.005) and type of tumour (p = 0.018) were demonstrated to have lower survival rates. CONCLUSION: Recurrence rate were significant predictor among patient with lymph node involvement and higher lymph node ratio, while stages of tumour, tumour grade, size of tumour and type of tumour were all highly significant predictor for survival rate. Therefore, the aim for early diagnosis and management of breast cancer is crucial in improving the treatment outcome. Elsevier 2022-09-02 /pmc/articles/PMC9486850/ /pubmed/36147066 http://dx.doi.org/10.1016/j.amsu.2022.104560 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Cohort Study Kumilau, Raynee Hayati, Firdaus Liew, Jerry ES. Sharif, Siti Zubaidah Sahid Nik Lah, Nik Amin Short term recurrence and survival rate of breast cancer patients post surgical treatment; north borneo experience |
title | Short term recurrence and survival rate of breast cancer patients post surgical treatment; north borneo experience |
title_full | Short term recurrence and survival rate of breast cancer patients post surgical treatment; north borneo experience |
title_fullStr | Short term recurrence and survival rate of breast cancer patients post surgical treatment; north borneo experience |
title_full_unstemmed | Short term recurrence and survival rate of breast cancer patients post surgical treatment; north borneo experience |
title_short | Short term recurrence and survival rate of breast cancer patients post surgical treatment; north borneo experience |
title_sort | short term recurrence and survival rate of breast cancer patients post surgical treatment; north borneo experience |
topic | Cohort Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9486850/ https://www.ncbi.nlm.nih.gov/pubmed/36147066 http://dx.doi.org/10.1016/j.amsu.2022.104560 |
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