Ullmann homocoupling of arenediazonium salts in a deep eutectic solvent. Synthetic and mechanistic aspects

A deep eutectic solvent (DES) based on glycerol and KF is successfully exploited as a solvent medium in Ullmann homocoupling of arenediazonium salts. The reactions were carried out in mild conditions and target products were obtained in fairly good yields. A computational study is presented aiming t...

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Autores principales: Ghigo, Giovanni, Bonomo, Matteo, Antenucci, Achille, Damin, Alessandro, Dughera, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487193/
https://www.ncbi.nlm.nih.gov/pubmed/36275154
http://dx.doi.org/10.1039/d2ra05272e
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author Ghigo, Giovanni
Bonomo, Matteo
Antenucci, Achille
Damin, Alessandro
Dughera, Stefano
author_facet Ghigo, Giovanni
Bonomo, Matteo
Antenucci, Achille
Damin, Alessandro
Dughera, Stefano
author_sort Ghigo, Giovanni
collection PubMed
description A deep eutectic solvent (DES) based on glycerol and KF is successfully exploited as a solvent medium in Ullmann homocoupling of arenediazonium salts. The reactions were carried out in mild conditions and target products were obtained in fairly good yields. A computational study is presented aiming to understand the reaction mechanism and Raman spectroscopy is employed as an experimental tool to support it.
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spelling pubmed-94871932022-10-20 Ullmann homocoupling of arenediazonium salts in a deep eutectic solvent. Synthetic and mechanistic aspects Ghigo, Giovanni Bonomo, Matteo Antenucci, Achille Damin, Alessandro Dughera, Stefano RSC Adv Chemistry A deep eutectic solvent (DES) based on glycerol and KF is successfully exploited as a solvent medium in Ullmann homocoupling of arenediazonium salts. The reactions were carried out in mild conditions and target products were obtained in fairly good yields. A computational study is presented aiming to understand the reaction mechanism and Raman spectroscopy is employed as an experimental tool to support it. The Royal Society of Chemistry 2022-09-20 /pmc/articles/PMC9487193/ /pubmed/36275154 http://dx.doi.org/10.1039/d2ra05272e Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Ghigo, Giovanni
Bonomo, Matteo
Antenucci, Achille
Damin, Alessandro
Dughera, Stefano
Ullmann homocoupling of arenediazonium salts in a deep eutectic solvent. Synthetic and mechanistic aspects
title Ullmann homocoupling of arenediazonium salts in a deep eutectic solvent. Synthetic and mechanistic aspects
title_full Ullmann homocoupling of arenediazonium salts in a deep eutectic solvent. Synthetic and mechanistic aspects
title_fullStr Ullmann homocoupling of arenediazonium salts in a deep eutectic solvent. Synthetic and mechanistic aspects
title_full_unstemmed Ullmann homocoupling of arenediazonium salts in a deep eutectic solvent. Synthetic and mechanistic aspects
title_short Ullmann homocoupling of arenediazonium salts in a deep eutectic solvent. Synthetic and mechanistic aspects
title_sort ullmann homocoupling of arenediazonium salts in a deep eutectic solvent. synthetic and mechanistic aspects
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487193/
https://www.ncbi.nlm.nih.gov/pubmed/36275154
http://dx.doi.org/10.1039/d2ra05272e
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