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A fundamental change emerging in locally advanced rectal cancer management: a case report

Treatment of locally advanced rectal cancer remains a challenge in colorectal surgery. It has had an evolving landscape over the past three decades. Implementation of total neoadjuvant therapy (TNT) as a novel approach to management has begun globally but long-term outcomes and data analysis to iden...

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Detalles Bibliográficos
Autores principales: Edwards-Murphy, Amy, Earley, Helen, Creavin, Ben, McCullough, Peter, Cooke, Fiachra, Neary, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487196/
https://www.ncbi.nlm.nih.gov/pubmed/36148143
http://dx.doi.org/10.1093/jscr/rjac405
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author Edwards-Murphy, Amy
Earley, Helen
Creavin, Ben
McCullough, Peter
Cooke, Fiachra
Neary, Peter
author_facet Edwards-Murphy, Amy
Earley, Helen
Creavin, Ben
McCullough, Peter
Cooke, Fiachra
Neary, Peter
author_sort Edwards-Murphy, Amy
collection PubMed
description Treatment of locally advanced rectal cancer remains a challenge in colorectal surgery. It has had an evolving landscape over the past three decades. Implementation of total neoadjuvant therapy (TNT) as a novel approach to management has begun globally but long-term outcomes and data analysis to identify optimal schedules are eagerly awaited. We report a case of locally advanced rectal cancer management in a young male with a complete pathological response to TNT.
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spelling pubmed-94871962022-09-21 A fundamental change emerging in locally advanced rectal cancer management: a case report Edwards-Murphy, Amy Earley, Helen Creavin, Ben McCullough, Peter Cooke, Fiachra Neary, Peter J Surg Case Rep Case Report Treatment of locally advanced rectal cancer remains a challenge in colorectal surgery. It has had an evolving landscape over the past three decades. Implementation of total neoadjuvant therapy (TNT) as a novel approach to management has begun globally but long-term outcomes and data analysis to identify optimal schedules are eagerly awaited. We report a case of locally advanced rectal cancer management in a young male with a complete pathological response to TNT. Oxford University Press 2022-09-19 /pmc/articles/PMC9487196/ /pubmed/36148143 http://dx.doi.org/10.1093/jscr/rjac405 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2022. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Edwards-Murphy, Amy
Earley, Helen
Creavin, Ben
McCullough, Peter
Cooke, Fiachra
Neary, Peter
A fundamental change emerging in locally advanced rectal cancer management: a case report
title A fundamental change emerging in locally advanced rectal cancer management: a case report
title_full A fundamental change emerging in locally advanced rectal cancer management: a case report
title_fullStr A fundamental change emerging in locally advanced rectal cancer management: a case report
title_full_unstemmed A fundamental change emerging in locally advanced rectal cancer management: a case report
title_short A fundamental change emerging in locally advanced rectal cancer management: a case report
title_sort fundamental change emerging in locally advanced rectal cancer management: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487196/
https://www.ncbi.nlm.nih.gov/pubmed/36148143
http://dx.doi.org/10.1093/jscr/rjac405
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