Molecular mechanisms of resistance in epidermal growth factor receptor-mutant lung adenocarcinomas

The discovery of epidermal growth factor receptor (EGFR) mutations in nonsmall cell lung cancer (NSCLC) has allowed the identification of a subset of patients whose tumours are exquisitely sensitive to EGFR tyrosine kinase inhibitors (TKIs). Despite the efficacy and superiority of EGFR TKIs over che...

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Detalles Bibliográficos
Autores principales: Cortot, Alexis B., Jänne, Pasi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2014
Materias:
Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487318/
https://www.ncbi.nlm.nih.gov/pubmed/25176972
http://dx.doi.org/10.1183/09059180.00004614

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