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Addressing unmet needs in the treatment of COPD

The burden of chronic obstructive pulmonary disease (COPD) is considerable, both socially and economically. Central to COPD management is the use of long-acting bronchodilators, which provide patients with optimal bronchodilation and improvements in symptoms. The once-daily, long-acting β(2)-agonist...

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Detalles Bibliográficos
Autores principales: Patalano, Francesco, Banerji, Donald, D’Andrea, Peter, Fogel, Robert, Altman, Pablo, Colthorpe, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487321/
https://www.ncbi.nlm.nih.gov/pubmed/25176969
http://dx.doi.org/10.1183/09059180.00004014
Descripción
Sumario:The burden of chronic obstructive pulmonary disease (COPD) is considerable, both socially and economically. Central to COPD management is the use of long-acting bronchodilators, which provide patients with optimal bronchodilation and improvements in symptoms. The once-daily, long-acting β(2)-agonist indacaterol, the long-acting muscarinic antagonist glycopyrronium, and the indacaterol/glycopyrronium fixed-dose combination QVA149 have all been shown to significantly improve lung function and patient-reported outcomes. The ability to take medication appropriately is important. Easy to use, low resistance devices may help patients take their medication and achieve good drug deposition. There is a need to optimise COPD management by treating the right patients with the right therapy at the right time during the course of their disease. Herein, we present a view on the current COPD management landscape and current unmet needs, and look to the future of COPD treatment and how patient care can be optimised.