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Addressing unmet needs in the treatment of COPD

The burden of chronic obstructive pulmonary disease (COPD) is considerable, both socially and economically. Central to COPD management is the use of long-acting bronchodilators, which provide patients with optimal bronchodilation and improvements in symptoms. The once-daily, long-acting β(2)-agonist...

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Autores principales: Patalano, Francesco, Banerji, Donald, D’Andrea, Peter, Fogel, Robert, Altman, Pablo, Colthorpe, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487321/
https://www.ncbi.nlm.nih.gov/pubmed/25176969
http://dx.doi.org/10.1183/09059180.00004014
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author Patalano, Francesco
Banerji, Donald
D’Andrea, Peter
Fogel, Robert
Altman, Pablo
Colthorpe, Paul
author_facet Patalano, Francesco
Banerji, Donald
D’Andrea, Peter
Fogel, Robert
Altman, Pablo
Colthorpe, Paul
author_sort Patalano, Francesco
collection PubMed
description The burden of chronic obstructive pulmonary disease (COPD) is considerable, both socially and economically. Central to COPD management is the use of long-acting bronchodilators, which provide patients with optimal bronchodilation and improvements in symptoms. The once-daily, long-acting β(2)-agonist indacaterol, the long-acting muscarinic antagonist glycopyrronium, and the indacaterol/glycopyrronium fixed-dose combination QVA149 have all been shown to significantly improve lung function and patient-reported outcomes. The ability to take medication appropriately is important. Easy to use, low resistance devices may help patients take their medication and achieve good drug deposition. There is a need to optimise COPD management by treating the right patients with the right therapy at the right time during the course of their disease. Herein, we present a view on the current COPD management landscape and current unmet needs, and look to the future of COPD treatment and how patient care can be optimised.
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spelling pubmed-94873212022-11-14 Addressing unmet needs in the treatment of COPD Patalano, Francesco Banerji, Donald D’Andrea, Peter Fogel, Robert Altman, Pablo Colthorpe, Paul Eur Respir Rev Reviews The burden of chronic obstructive pulmonary disease (COPD) is considerable, both socially and economically. Central to COPD management is the use of long-acting bronchodilators, which provide patients with optimal bronchodilation and improvements in symptoms. The once-daily, long-acting β(2)-agonist indacaterol, the long-acting muscarinic antagonist glycopyrronium, and the indacaterol/glycopyrronium fixed-dose combination QVA149 have all been shown to significantly improve lung function and patient-reported outcomes. The ability to take medication appropriately is important. Easy to use, low resistance devices may help patients take their medication and achieve good drug deposition. There is a need to optimise COPD management by treating the right patients with the right therapy at the right time during the course of their disease. Herein, we present a view on the current COPD management landscape and current unmet needs, and look to the future of COPD treatment and how patient care can be optimised. European Respiratory Society 2014-09 /pmc/articles/PMC9487321/ /pubmed/25176969 http://dx.doi.org/10.1183/09059180.00004014 Text en ©ERS 2014 https://creativecommons.org/licenses/by-nc/4.0/ERR articles are open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0 (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Reviews
Patalano, Francesco
Banerji, Donald
D’Andrea, Peter
Fogel, Robert
Altman, Pablo
Colthorpe, Paul
Addressing unmet needs in the treatment of COPD
title Addressing unmet needs in the treatment of COPD
title_full Addressing unmet needs in the treatment of COPD
title_fullStr Addressing unmet needs in the treatment of COPD
title_full_unstemmed Addressing unmet needs in the treatment of COPD
title_short Addressing unmet needs in the treatment of COPD
title_sort addressing unmet needs in the treatment of copd
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487321/
https://www.ncbi.nlm.nih.gov/pubmed/25176969
http://dx.doi.org/10.1183/09059180.00004014
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