A Review of Humoral and Cellular Immune Responses to SARS-CoV-2 Vaccination Following Solid Organ Transplantation

The introduction of vaccines preventing a severe course of COVID-19 disease is particularly important in immunocompromised patients, among whom organ recipients and patients awaiting transplantation constitute a large group. The article is a critical review of 68 recent publications on the impact of...

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Autores principales: Cieślak, Ilona, Kwapisz, Magdalena, Tronina, Olga, Gotlib, Joanna, Lisik, Wojciech, Wasiak, Dariusz, Hreńczuk, Marta, Rahnama, Mansur, Małkowski, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2022
Materias:
Review Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487342/
https://www.ncbi.nlm.nih.gov/pubmed/36110033
http://dx.doi.org/10.12659/AOT.936949
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author Cieślak, Ilona
Kwapisz, Magdalena
Tronina, Olga
Gotlib, Joanna
Lisik, Wojciech
Wasiak, Dariusz
Hreńczuk, Marta
Rahnama, Mansur
Małkowski, Piotr
author_facet Cieślak, Ilona
Kwapisz, Magdalena
Tronina, Olga
Gotlib, Joanna
Lisik, Wojciech
Wasiak, Dariusz
Hreńczuk, Marta
Rahnama, Mansur
Małkowski, Piotr
author_sort Cieślak, Ilona
collection PubMed
description The introduction of vaccines preventing a severe course of COVID-19 disease is particularly important in immunocompromised patients, among whom organ recipients and patients awaiting transplantation constitute a large group. The article is a critical review of 68 recent publications on the impact of the SARS-CoV-2 pandemic on transplantology worldwide. The study discusses research results concerning various aspects of SARS-CoV-2 vaccination in transplant patients; it also lists important factors influencing vaccination effectiveness. A suboptimal immune response to 2 doses of vaccine in this group of patients is a major challenge prompting further research. Therefore, this review aims to provide an update on the humoral and cellular immune responses to SARS-CoV-2 vaccination following solid organ transplantation.
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spelling pubmed-94873422022-10-20 A Review of Humoral and Cellular Immune Responses to SARS-CoV-2 Vaccination Following Solid Organ Transplantation Cieślak, Ilona Kwapisz, Magdalena Tronina, Olga Gotlib, Joanna Lisik, Wojciech Wasiak, Dariusz Hreńczuk, Marta Rahnama, Mansur Małkowski, Piotr Ann Transplant Review Paper The introduction of vaccines preventing a severe course of COVID-19 disease is particularly important in immunocompromised patients, among whom organ recipients and patients awaiting transplantation constitute a large group. The article is a critical review of 68 recent publications on the impact of the SARS-CoV-2 pandemic on transplantology worldwide. The study discusses research results concerning various aspects of SARS-CoV-2 vaccination in transplant patients; it also lists important factors influencing vaccination effectiveness. A suboptimal immune response to 2 doses of vaccine in this group of patients is a major challenge prompting further research. Therefore, this review aims to provide an update on the humoral and cellular immune responses to SARS-CoV-2 vaccination following solid organ transplantation. International Scientific Literature, Inc. 2022-09-16 /pmc/articles/PMC9487342/ /pubmed/36110033 http://dx.doi.org/10.12659/AOT.936949 Text en © Ann Transplant, 2022 https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Review Paper
Cieślak, Ilona
Kwapisz, Magdalena
Tronina, Olga
Gotlib, Joanna
Lisik, Wojciech
Wasiak, Dariusz
Hreńczuk, Marta
Rahnama, Mansur
Małkowski, Piotr
A Review of Humoral and Cellular Immune Responses to SARS-CoV-2 Vaccination Following Solid Organ Transplantation
title A Review of Humoral and Cellular Immune Responses to SARS-CoV-2 Vaccination Following Solid Organ Transplantation
title_full A Review of Humoral and Cellular Immune Responses to SARS-CoV-2 Vaccination Following Solid Organ Transplantation
title_fullStr A Review of Humoral and Cellular Immune Responses to SARS-CoV-2 Vaccination Following Solid Organ Transplantation
title_full_unstemmed A Review of Humoral and Cellular Immune Responses to SARS-CoV-2 Vaccination Following Solid Organ Transplantation
title_short A Review of Humoral and Cellular Immune Responses to SARS-CoV-2 Vaccination Following Solid Organ Transplantation
title_sort review of humoral and cellular immune responses to sars-cov-2 vaccination following solid organ transplantation
topic Review Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487342/
https://www.ncbi.nlm.nih.gov/pubmed/36110033
http://dx.doi.org/10.12659/AOT.936949
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