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Refinement of computational identification of somatic copy number alterations using DNA methylation microarrays illustrated in cancers of unknown primary

High-throughput genomic technologies are increasingly used in personalized cancer medicine. However, computational tools to maximize the use of scarce tissues combining distinct molecular layers are needed. Here we present a refined strategy, based on the R-package ‘conumee’, to better predict somat...

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Detalles Bibliográficos
Autores principales: Blecua, Pedro, Davalos, Veronica, de Villasante, Izar, Merkel, Angelika, Musulen, Eva, Coll-SanMartin, Laia, Esteller, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487591/
https://www.ncbi.nlm.nih.gov/pubmed/35524475
http://dx.doi.org/10.1093/bib/bbac161