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Balancing the transcriptome: leveraging sample similarity to improve measures of gene specificity
The spatial and temporal domain of a gene’s expression can range from ubiquitous to highly specific. Quantifying the degree to which this expression is unique to a specific tissue or developmental timepoint can provide insight into the etiology of genetic diseases. However, quantifying specificity r...
Autores principales: | Bondhus, Leroy, Varma, Roshni, Hernandez, Yenifer, Arboleda, Valerie A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487600/ https://www.ncbi.nlm.nih.gov/pubmed/35534150 http://dx.doi.org/10.1093/bib/bbac158 |
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