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KRAS oncogene in lung cancer: focus on molecularly driven clinical trials

KRAS mutations are the most frequent molecular abnormalities found in one out of four nonsmall cell lung cancers (NSCLC). Their incidence increases in cases of adenocarcinoma, smokers and Caucasian patients. Their negative value in terms of prognosis and responsiveness to both standard chemotherapy...

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Detalles Bibliográficos
Autores principales: Kempf, Emmanuelle, Rousseau, Benoît, Besse, Benjamin, Paz-Ares, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487658/
https://www.ncbi.nlm.nih.gov/pubmed/26929424
http://dx.doi.org/10.1183/16000617.0071-2015