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Radio(chemo)therapy in locally advanced nonsmall cell lung cancer

Definitive radiochemotherapy is the standard treatment for many patients with locally advanced nonsmall cell lung cancer (NSCLC). Treatment outcomes have improved over the last decades. Several treatment regimens have been shown effective and safe. This review summarises the results of significant s...

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Autores principales: Glatzer, Markus, Elicin, Olgun, Ramella, Sara, Nestle, Ursula, Putora, Paul Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487664/
https://www.ncbi.nlm.nih.gov/pubmed/26929423
http://dx.doi.org/10.1183/16000617.0053-2015
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author Glatzer, Markus
Elicin, Olgun
Ramella, Sara
Nestle, Ursula
Putora, Paul Martin
author_facet Glatzer, Markus
Elicin, Olgun
Ramella, Sara
Nestle, Ursula
Putora, Paul Martin
author_sort Glatzer, Markus
collection PubMed
description Definitive radiochemotherapy is the standard treatment for many patients with locally advanced nonsmall cell lung cancer (NSCLC). Treatment outcomes have improved over the last decades. Several treatment regimens have been shown effective and safe. This review summarises the results of significant studies between 1996 and 2015 on concomitant and sequential radiochemotherapy regimens and radiation dose per fraction. Beside therapy regimens, optimised radiotherapy planning is indispensable to improve outcome and minimise radiation-induced toxicity. An insight into the rationale of radiotherapy planning for stage III NSCLC is also provided.
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spelling pubmed-94876642022-11-14 Radio(chemo)therapy in locally advanced nonsmall cell lung cancer Glatzer, Markus Elicin, Olgun Ramella, Sara Nestle, Ursula Putora, Paul Martin Eur Respir Rev Reviews Definitive radiochemotherapy is the standard treatment for many patients with locally advanced nonsmall cell lung cancer (NSCLC). Treatment outcomes have improved over the last decades. Several treatment regimens have been shown effective and safe. This review summarises the results of significant studies between 1996 and 2015 on concomitant and sequential radiochemotherapy regimens and radiation dose per fraction. Beside therapy regimens, optimised radiotherapy planning is indispensable to improve outcome and minimise radiation-induced toxicity. An insight into the rationale of radiotherapy planning for stage III NSCLC is also provided. European Respiratory Society 2016-03 2016-02-09 /pmc/articles/PMC9487664/ /pubmed/26929423 http://dx.doi.org/10.1183/16000617.0053-2015 Text en Copyright ©ERS 2016. https://creativecommons.org/licenses/by-nc/4.0/ERR articles are open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.
spellingShingle Reviews
Glatzer, Markus
Elicin, Olgun
Ramella, Sara
Nestle, Ursula
Putora, Paul Martin
Radio(chemo)therapy in locally advanced nonsmall cell lung cancer
title Radio(chemo)therapy in locally advanced nonsmall cell lung cancer
title_full Radio(chemo)therapy in locally advanced nonsmall cell lung cancer
title_fullStr Radio(chemo)therapy in locally advanced nonsmall cell lung cancer
title_full_unstemmed Radio(chemo)therapy in locally advanced nonsmall cell lung cancer
title_short Radio(chemo)therapy in locally advanced nonsmall cell lung cancer
title_sort radio(chemo)therapy in locally advanced nonsmall cell lung cancer
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487664/
https://www.ncbi.nlm.nih.gov/pubmed/26929423
http://dx.doi.org/10.1183/16000617.0053-2015
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