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Methylation of FKBP5 is associated with accelerated DNA methylation ageing and cardiometabolic risk: replication in young-adult and middle-aged Black Americans

Methylation of FKBP5 is involved in the regulation of the stress response and is influenced by early stress exposure. Two CpG sites, cg20813374 and cg00130530, have been identified as potential reporters of early stress. We examined whether FKBP5 methylation was associated with accelerated DNA methy...

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Detalles Bibliográficos
Autores principales: Beach, Steven R. H., Ong, Mei Ling, Lei, Man-Kit, Carter, Sierra E., Simons, Ronald L., Gibbons, Frederick X., Philibert, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487733/
https://www.ncbi.nlm.nih.gov/pubmed/34533092
http://dx.doi.org/10.1080/15592294.2021.1980688