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Polyphyllin II induced apoptosis of NSCLC cells by inhibiting autophagy through the mTOR pathway
CONTEXT: Polyphyllin II (PPII) is a steroidal saponin isolated from Rhizoma Paridis. It exhibits significant antitumor activity such as anti-proliferation and pro-apoptosis in lung cancer. OBJECTIVE: To explore whether PPII induce autophagy and the relationship between autophagy and apoptosis in non...
Autores principales: | Jiao, Yuhan, Xin, Ming, Xu, Juanjuan, Xiang, Xindong, Li, Xuan, Jiang, Jingjing, Jia, Xiuqin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487979/ https://www.ncbi.nlm.nih.gov/pubmed/36102594 http://dx.doi.org/10.1080/13880209.2022.2120021 |
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