Single-cell RNA sequencing reveals dysregulation of spinal cord cell types in a severe spinal muscular atrophy mouse model

Although spinal muscular atrophy (SMA) is a motor neuron disease caused by the loss of survival of motor neuron (SMN) proteins, there is growing evidence that non-neuronal cells play important roles in SMA pathogenesis. However, transcriptome alterations occurring at the single-cell level in SMA spi...

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Detalles Bibliográficos
Autores principales: Sun, Junjie, Qiu, Jiaying, Yang, Qiongxia, Ju, Qianqian, Qu, Ruobing, Wang, Xu, Wu, Liucheng, Xing, Lingyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488758/
https://www.ncbi.nlm.nih.gov/pubmed/36074806
http://dx.doi.org/10.1371/journal.pgen.1010392

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