The histone deacetylase inhibitor M344 as a multifaceted therapy for pancreatic cancer

The histone deacetylase (HDAC) inhibitor vorinostat, used with gemcitabine and other therapies, has been effective in treatment of experimental models of pancreatic cancer. In this study, we demonstrated that M344, an HDAC inhibitor, is efficacious against pancreatic cancer in vitro and in vivo, alo...

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Detalles Bibliográficos
Autores principales: Knoche, Shelby M., Brumfield, Gabrielle L., Goetz, Benjamin T., Sliker, Bailee H., Larson, Alaina C., Olson, Madeline T., Poelaert, Brittany J., Bavari, Audrey, Yan, Ying, Black, Jennifer D., Solheim, Joyce C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488834/
https://www.ncbi.nlm.nih.gov/pubmed/36126055
http://dx.doi.org/10.1371/journal.pone.0273518

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