Cargando…

State-controlled epidemic in a game against a novel pathogen

The pandemic reminded us that the pathogen evolution still has a serious effect on human societies. States, however, can prepare themselves for the emergence of a novel pathogen with unknown characteristics by analysing potential scenarios. Game theory offers such an appropriate tool. In our game-th...

Descripción completa

Detalles Bibliográficos
Autores principales: Garay, József, Kun, Ádám, Varga, Zoltán, Gámez, Manuel, Castaño-Fernández, Ana Belén, Móri, Tamás F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488893/
https://www.ncbi.nlm.nih.gov/pubmed/36127449
http://dx.doi.org/10.1038/s41598-022-19691-7
_version_ 1784792762614284288
author Garay, József
Kun, Ádám
Varga, Zoltán
Gámez, Manuel
Castaño-Fernández, Ana Belén
Móri, Tamás F.
author_facet Garay, József
Kun, Ádám
Varga, Zoltán
Gámez, Manuel
Castaño-Fernández, Ana Belén
Móri, Tamás F.
author_sort Garay, József
collection PubMed
description The pandemic reminded us that the pathogen evolution still has a serious effect on human societies. States, however, can prepare themselves for the emergence of a novel pathogen with unknown characteristics by analysing potential scenarios. Game theory offers such an appropriate tool. In our game-theoretical framework, the state is playing against a pathogen by introducing non-pharmaceutical interventions to fulfil its socio-political goals, such as guaranteeing hospital care to all needed patients, keeping the country functioning, while the applied social restrictions should be as soft as possible. With the inclusion of activity and economic sector dependent transmission rate, optimal control of lockdowns and health care capacity management is calculated. We identify the presence and length of a pre-symptomatic infectious stage of the disease to have the greatest effect on the probability to cause a pandemic. Here we show that contrary to intuition, the state should not strive for the great expansion of its health care capacities even if its goal is to provide care for all requiring it and minimize the cost of lockdowns.
format Online
Article
Text
id pubmed-9488893
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-94888932022-09-21 State-controlled epidemic in a game against a novel pathogen Garay, József Kun, Ádám Varga, Zoltán Gámez, Manuel Castaño-Fernández, Ana Belén Móri, Tamás F. Sci Rep Article The pandemic reminded us that the pathogen evolution still has a serious effect on human societies. States, however, can prepare themselves for the emergence of a novel pathogen with unknown characteristics by analysing potential scenarios. Game theory offers such an appropriate tool. In our game-theoretical framework, the state is playing against a pathogen by introducing non-pharmaceutical interventions to fulfil its socio-political goals, such as guaranteeing hospital care to all needed patients, keeping the country functioning, while the applied social restrictions should be as soft as possible. With the inclusion of activity and economic sector dependent transmission rate, optimal control of lockdowns and health care capacity management is calculated. We identify the presence and length of a pre-symptomatic infectious stage of the disease to have the greatest effect on the probability to cause a pandemic. Here we show that contrary to intuition, the state should not strive for the great expansion of its health care capacities even if its goal is to provide care for all requiring it and minimize the cost of lockdowns. Nature Publishing Group UK 2022-09-20 /pmc/articles/PMC9488893/ /pubmed/36127449 http://dx.doi.org/10.1038/s41598-022-19691-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Garay, József
Kun, Ádám
Varga, Zoltán
Gámez, Manuel
Castaño-Fernández, Ana Belén
Móri, Tamás F.
State-controlled epidemic in a game against a novel pathogen
title State-controlled epidemic in a game against a novel pathogen
title_full State-controlled epidemic in a game against a novel pathogen
title_fullStr State-controlled epidemic in a game against a novel pathogen
title_full_unstemmed State-controlled epidemic in a game against a novel pathogen
title_short State-controlled epidemic in a game against a novel pathogen
title_sort state-controlled epidemic in a game against a novel pathogen
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488893/
https://www.ncbi.nlm.nih.gov/pubmed/36127449
http://dx.doi.org/10.1038/s41598-022-19691-7
work_keys_str_mv AT garayjozsef statecontrolledepidemicinagameagainstanovelpathogen
AT kunadam statecontrolledepidemicinagameagainstanovelpathogen
AT vargazoltan statecontrolledepidemicinagameagainstanovelpathogen
AT gamezmanuel statecontrolledepidemicinagameagainstanovelpathogen
AT castanofernandezanabelen statecontrolledepidemicinagameagainstanovelpathogen
AT moritamasf statecontrolledepidemicinagameagainstanovelpathogen