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State-controlled epidemic in a game against a novel pathogen
The pandemic reminded us that the pathogen evolution still has a serious effect on human societies. States, however, can prepare themselves for the emergence of a novel pathogen with unknown characteristics by analysing potential scenarios. Game theory offers such an appropriate tool. In our game-th...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488893/ https://www.ncbi.nlm.nih.gov/pubmed/36127449 http://dx.doi.org/10.1038/s41598-022-19691-7 |
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author | Garay, József Kun, Ádám Varga, Zoltán Gámez, Manuel Castaño-Fernández, Ana Belén Móri, Tamás F. |
author_facet | Garay, József Kun, Ádám Varga, Zoltán Gámez, Manuel Castaño-Fernández, Ana Belén Móri, Tamás F. |
author_sort | Garay, József |
collection | PubMed |
description | The pandemic reminded us that the pathogen evolution still has a serious effect on human societies. States, however, can prepare themselves for the emergence of a novel pathogen with unknown characteristics by analysing potential scenarios. Game theory offers such an appropriate tool. In our game-theoretical framework, the state is playing against a pathogen by introducing non-pharmaceutical interventions to fulfil its socio-political goals, such as guaranteeing hospital care to all needed patients, keeping the country functioning, while the applied social restrictions should be as soft as possible. With the inclusion of activity and economic sector dependent transmission rate, optimal control of lockdowns and health care capacity management is calculated. We identify the presence and length of a pre-symptomatic infectious stage of the disease to have the greatest effect on the probability to cause a pandemic. Here we show that contrary to intuition, the state should not strive for the great expansion of its health care capacities even if its goal is to provide care for all requiring it and minimize the cost of lockdowns. |
format | Online Article Text |
id | pubmed-9488893 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-94888932022-09-21 State-controlled epidemic in a game against a novel pathogen Garay, József Kun, Ádám Varga, Zoltán Gámez, Manuel Castaño-Fernández, Ana Belén Móri, Tamás F. Sci Rep Article The pandemic reminded us that the pathogen evolution still has a serious effect on human societies. States, however, can prepare themselves for the emergence of a novel pathogen with unknown characteristics by analysing potential scenarios. Game theory offers such an appropriate tool. In our game-theoretical framework, the state is playing against a pathogen by introducing non-pharmaceutical interventions to fulfil its socio-political goals, such as guaranteeing hospital care to all needed patients, keeping the country functioning, while the applied social restrictions should be as soft as possible. With the inclusion of activity and economic sector dependent transmission rate, optimal control of lockdowns and health care capacity management is calculated. We identify the presence and length of a pre-symptomatic infectious stage of the disease to have the greatest effect on the probability to cause a pandemic. Here we show that contrary to intuition, the state should not strive for the great expansion of its health care capacities even if its goal is to provide care for all requiring it and minimize the cost of lockdowns. Nature Publishing Group UK 2022-09-20 /pmc/articles/PMC9488893/ /pubmed/36127449 http://dx.doi.org/10.1038/s41598-022-19691-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Garay, József Kun, Ádám Varga, Zoltán Gámez, Manuel Castaño-Fernández, Ana Belén Móri, Tamás F. State-controlled epidemic in a game against a novel pathogen |
title | State-controlled epidemic in a game against a novel pathogen |
title_full | State-controlled epidemic in a game against a novel pathogen |
title_fullStr | State-controlled epidemic in a game against a novel pathogen |
title_full_unstemmed | State-controlled epidemic in a game against a novel pathogen |
title_short | State-controlled epidemic in a game against a novel pathogen |
title_sort | state-controlled epidemic in a game against a novel pathogen |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488893/ https://www.ncbi.nlm.nih.gov/pubmed/36127449 http://dx.doi.org/10.1038/s41598-022-19691-7 |
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