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Genomic Classification of HER2-Positive Patients With 80-Gene and 70-Gene Signatures Identifies Diversity in Clinical Outcomes With HER2-Targeted Neoadjuvant Therapy

The prospective Neoadjuvant Breast Registry Symphony Trial compared the 80-gene molecular subtyping signature with clinical assessment by immunohistochemistry and/or fluorescence in situ hybridization in predicting pathologic complete response (pCR) and 5-year outcomes in patients with early-stage b...

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Detalles Bibliográficos
Autores principales: Whitworth, Pat W., Beitsch, Peter D., Murray, Mary K., Richards, Paul D., Mislowsky, Angela, Dul, Carrie L., Pellicane, James V., Baron, Paul L., Rahman, Rakhshanda Layeequr, Lee, Laura A., Dupree, Beth B., Kelemen, Pond R., Ashikari, Andrew Y., Budway, Raye J., Lopez-Penalver, Cristina, Dooley, William, Wang, Shiyu, Dauer, Patricia, Menicucci, Andrea R., Yoder, Erin B., Finn, Christine, Blumencranz, Lisa E., Audeh, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489196/
https://www.ncbi.nlm.nih.gov/pubmed/36108259
http://dx.doi.org/10.1200/PO.22.00197