Mechanism of bisphosphonate-related osteonecrosis of the jaw (BRONJ) revealed by targeted removal of legacy bisphosphonate from jawbone using competing inert hydroxymethylene diphosphonate

Bisphosphonate-related osteonecrosis of the jaw (BRONJ) presents as a morbid jawbone lesion in patients exposed to a nitrogen-containing bisphosphonate (N-BP). Although it is rare, BRONJ has caused apprehension among patients and healthcare providers and decreased acceptance of this antiresorptive d...

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Detalles Bibliográficos
Autores principales: Okawa, Hiroko, Kondo, Takeru, Hokugo, Akishige, Cherian, Philip, Campagna, Jesus J, Lentini, Nicholas A, Sung, Eric C, Chiang, Samantha, Lin, Yi-Ling, Ebetino, Frank H, John, Varghese, Sun, Shuting, McKenna, Charles E, Nishimura, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489207/
https://www.ncbi.nlm.nih.gov/pubmed/36017995
http://dx.doi.org/10.7554/eLife.76207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489207/
https://www.ncbi.nlm.nih.gov/pubmed/36017995
http://dx.doi.org/10.7554/eLife.76207

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