Cargando…
EGCG Enhances the Chemosensitivity of Colorectal Cancer to Irinotecan through GRP78-MediatedEndoplasmic Reticulum Stress
This study aimed to explore the role of GRP78-mediated endoplasmic reticulum stress (ERS) in the synergistic inhibition of colorectal cancer by epigallocatechin-3-gallate (EGCG) and irinotecan (IRI). Findings showed that EGCG alone or in combination with irinotecan can significantly promote intracel...
Autores principales: | Wu, Wenbing, Gou, Hui, Xiang, Bin, Geng, Ruiman, Dong, Jingying, Yang, Xiaolong, Chen, Dan, Dai, Rongyang, Chen, Lihong, Liu, Ji |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489388/ https://www.ncbi.nlm.nih.gov/pubmed/36147440 http://dx.doi.org/10.1155/2022/7099589 |
Ejemplares similares
-
EGCG synergizes the therapeutic effect of irinotecan through enhanced DNA damage in human colorectal cancer cells
por: Wu, Wenbing, et al.
Publicado: (2021) -
Secretion of the endoplasmic reticulum stress protein, GRP78, into the BALF is increased in cigarette smokers
por: Aksoy, Mark O., et al.
Publicado: (2017) -
Endoplasmic reticulum chaperone GRP78 mediates cigarette smoke-induced necroptosis and injury in bronchial epithelium
por: Wang, Yong, et al.
Publicado: (2018) -
The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo
por: Park, Kyung-Won, et al.
Publicado: (2017) -
Mild Endoplasmic Reticulum Stress Promotes Retinal Neovascularization via Induction of BiP/GRP78
por: Nakamura, Shinsuke, et al.
Publicado: (2013)