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Fanconi Syndrome Induced by Tenofovir in a Diabetic Patient with a History of Chronic Hepatitis B: A Case Report

Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor and has been extensively used in the first-line treatment of viral infectious diseases such as chronic hepatitis B. Despite its good safety, the development of Fanconi syndrome is a rare adverse effect of long-term tenofov...

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Autores principales: Saremi, Zeinab, Fakharian, Tahereh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Association of Gastroerterology and Hepatology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489451/
https://www.ncbi.nlm.nih.gov/pubmed/36606019
http://dx.doi.org/10.34172/mejdd.2021.250
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author Saremi, Zeinab
Fakharian, Tahereh
author_facet Saremi, Zeinab
Fakharian, Tahereh
author_sort Saremi, Zeinab
collection PubMed
description Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor and has been extensively used in the first-line treatment of viral infectious diseases such as chronic hepatitis B. Despite its good safety, the development of Fanconi syndrome is a rare adverse effect of long-term tenofovir therapy. Here, we report a case of a 62-year-old diabetic woman with a history of chronic hepatitis B who was exposed to tenofovir and developed drug-associated Fanconi syndrome. After discounting tenofovir, the patient’s bone pain was markedly reduced.
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spelling pubmed-94894512023-01-04 Fanconi Syndrome Induced by Tenofovir in a Diabetic Patient with a History of Chronic Hepatitis B: A Case Report Saremi, Zeinab Fakharian, Tahereh Middle East J Dig Dis Case Report Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor and has been extensively used in the first-line treatment of viral infectious diseases such as chronic hepatitis B. Despite its good safety, the development of Fanconi syndrome is a rare adverse effect of long-term tenofovir therapy. Here, we report a case of a 62-year-old diabetic woman with a history of chronic hepatitis B who was exposed to tenofovir and developed drug-associated Fanconi syndrome. After discounting tenofovir, the patient’s bone pain was markedly reduced. Iranian Association of Gastroerterology and Hepatology 2021-10 2022-01-27 /pmc/articles/PMC9489451/ /pubmed/36606019 http://dx.doi.org/10.34172/mejdd.2021.250 Text en © 2021 The Author(s). https://creativecommons.org/licenses/by-nc/4.0/ This work is published by Middle East Journal of Digestive Diseases as an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ). Non-commercial uses of the work are permitted, provided the original work is properly cited.
spellingShingle Case Report
Saremi, Zeinab
Fakharian, Tahereh
Fanconi Syndrome Induced by Tenofovir in a Diabetic Patient with a History of Chronic Hepatitis B: A Case Report
title Fanconi Syndrome Induced by Tenofovir in a Diabetic Patient with a History of Chronic Hepatitis B: A Case Report
title_full Fanconi Syndrome Induced by Tenofovir in a Diabetic Patient with a History of Chronic Hepatitis B: A Case Report
title_fullStr Fanconi Syndrome Induced by Tenofovir in a Diabetic Patient with a History of Chronic Hepatitis B: A Case Report
title_full_unstemmed Fanconi Syndrome Induced by Tenofovir in a Diabetic Patient with a History of Chronic Hepatitis B: A Case Report
title_short Fanconi Syndrome Induced by Tenofovir in a Diabetic Patient with a History of Chronic Hepatitis B: A Case Report
title_sort fanconi syndrome induced by tenofovir in a diabetic patient with a history of chronic hepatitis b: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489451/
https://www.ncbi.nlm.nih.gov/pubmed/36606019
http://dx.doi.org/10.34172/mejdd.2021.250
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