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Generation of Human iPSC-Derived Astrocytes with a mature star-shaped phenotype for CNS modeling

The generation of astrocytes from human induced pluripotent stem cells has been hampered by either prolonged differentiation—spanning over two months—or by shorter protocols that generate immature astrocytes, devoid of salient mature astrocytic traits pivotal for central nervous system (CNS) modelin...

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Detalles Bibliográficos
Autores principales: Voulgaris, Dimitrios, Nikolakopoulou, Polyxeni, Herland, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489586/
https://www.ncbi.nlm.nih.gov/pubmed/35488987
http://dx.doi.org/10.1007/s12015-022-10376-2