Cargando…
Intact HIV Proviruses Persist in the Brain Despite Viral Suppression with ART
OBJECTIVE: Human immunodeficiency virus (HIV) persistence in blood and tissue reservoirs, including the brain, is a major barrier to HIV cure and possible cause of comorbid disease. However, the size and replication competent nature of the central nervous system (CNS) reservoir is unclear. Here, we...
Autores principales: | Cochrane, Catherine R., Angelovich, Thomas A., Byrnes, Sarah J., Waring, Emily, Guanizo, Aleks C., Trollope, Gemma S., Zhou, Jingling, Vue, Judith, Senior, Lachlan, Wanicek, Emma, Eddine, Janna Jamal, Gartner, Matthew J., Jenkins, Trisha A., Gorry, Paul R., Brew, Bruce J., Lewin, Sharon R., Estes, Jacob D., Roche, Michael, Churchill, Melissa J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489665/ https://www.ncbi.nlm.nih.gov/pubmed/35867351 http://dx.doi.org/10.1002/ana.26456 |
Ejemplares similares
-
Non-Human Primate Models of HIV Brain Infection and Cognitive Disorders
por: Byrnes, Sarah J., et al.
Publicado: (2022) -
The role of oxidative stress in HIV-associated neurocognitive disorders
por: Buckley, Sarah, et al.
Publicado: (2021) -
Adaptation of the intact proviral DNA assay to a nanowell-based digital PCR platform
por: Tumpach, Carolin, et al.
Publicado: (2023) -
Longitudinal analysis of subtype C envelope tropism for memory CD4(+) T cell subsets over the first 3 years of untreated HIV-1 infection
por: Gartner, Matthew J., et al.
Publicado: (2020) -
Chronic immune activation and gut barrier dysfunction is associated with neuroinflammation in ART-suppressed SIV+ rhesus macaques
por: Byrnes, Sarah J., et al.
Publicado: (2023)