Cargando…

Construction of a trio-based structural variation panel utilizing activated T lymphocytes and long-read sequencing technology

Long-read sequencing technology enable better characterization of structural variants (SVs). To adapt the technology to population-scale analyses, one critical issue is to obtain sufficient amount of high-molecular-weight genomic DNA. Here, we propose utilizing activated T lymphocytes, which can be...

Descripción completa

Detalles Bibliográficos
Autores principales:	Otsuki, Akihito, Okamura, Yasunobu, Ishida, Noriko, Tadaka, Shu, Takayama, Jun, Kumada, Kazuki, Kawashima, Junko, Taguchi, Keiko, Minegishi, Naoko, Kuriyama, Shinichi, Tamiya, Gen, Kinoshita, Kengo, Katsuoka, Fumiki, Yamamoto, Masayuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489684/ https://www.ncbi.nlm.nih.gov/pubmed/36127505 http://dx.doi.org/10.1038/s42003-022-03953-1

Ejemplares similares

Construction and integration of three de novo Japanese human genome assemblies toward a population-specific reference
por: Takayama, Jun, et al.
Publicado: (2021)

jMorp updates in 2020: large enhancement of multi-omics data resources on the general Japanese population
por: Tadaka, Shu, et al.
Publicado: (2020)

A genotype imputation method for de-identified haplotype reference information by using recurrent neural network
por: Kojima, Kaname, et al.
Publicado: (2020)

Identification of critical genetic variants associated with metabolic phenotypes of the Japanese population
por: Koshiba, Seizo, et al.
Publicado: (2020)

3.5KJPNv2: an allele frequency panel of 3552 Japanese individuals including the X chromosome
por: Tadaka, Shu, et al.
Publicado: (2019)

ATTED-II in 2016: A Plant Coexpression Database Towards Lineage-Specific Coexpression
por: Aoki, Yuichi, et al.
Publicado: (2016)

Establishment of Integrated Biobank for Precision Medicine and Personalized Healthcare: The Tohoku Medical Megabank Project
por: Fuse, Nobuo, et al.
Publicado: (2019)

Japonica Array NEO with increased genome-wide coverage and abundant disease risk SNPs
por: Sakurai-Yageta, Mika, et al.
Publicado: (2021)

COXPRESdb: a database of comparative gene coexpression networks of eleven species for mammals
por: Obayashi, Takeshi, et al.
Publicado: (2013)

ATTED-II in 2014: Evaluation of Gene Coexpression in Agriculturally Important Plants
por: Obayashi, Takeshi, et al.
Publicado: (2014)

COXPRESdb in 2015: coexpression database for animal species by DNA-microarray and RNAseq-based expression data with multiple quality assessment systems
por: Okamura, Yasunobu, et al.
Publicado: (2014)

Regional genetic differences among Japanese populations and performance of genotype imputation using whole-genome reference panel of the Tohoku Medical Megabank Project
por: Yasuda, Jun, et al.
Publicado: (2018)

Construction of full-length Japanese reference panel of class I HLA genes with single-molecule, real-time sequencing
por: Mimori, Takahiro, et al.
Publicado: (2018)

Novel candidates of pathogenic variants of the BRCA1 and BRCA2 genes from a dataset of 3,552 Japanese whole genomes (3.5KJPNv2)
por: Tokunaga, Hideki, et al.
Publicado: (2021)

Matataki: an ultrafast mRNA quantification method for large-scale reanalysis of RNA-Seq data
por: Okamura, Yasunobu, et al.
Publicado: (2018)

Maternity Log study: a longitudinal lifelog monitoring and multiomics analysis for the early prediction of complicated pregnancy
por: Sugawara, Junichi, et al.
Publicado: (2019)

Selective Elimination of NRF2-Activated Cells by Competition With Neighboring Cells in the Esophageal Epithelium
por: Hirose, Wataru, et al.
Publicado: (2022)

Nrf2 alleviates spaceflight-induced immunosuppression and thrombotic microangiopathy in mice
por: Shimizu, Ritsuko, et al.
Publicado: (2023)

Comparison of Gene Coexpression Profiles and Construction of Conserved Gene Networks to Find Functional Modules
por: Okamura, Yasunobu, et al.
Publicado: (2015)

NCMine: Core-peripheral based functional module detection using near-clique mining
por: Tadaka, Shu, et al.
Publicado: (2016)

Construction of JRG (Japanese reference genome) with single-molecule real-time sequencing
por: Nagasaki, Masao, et al.
Publicado: (2019)

Analysis of HLA-G long-read genomic sequences in mother–offspring pairs with preeclampsia
por: Nishizawa, Ayako, et al.
Publicado: (2020)

Estimation of the carrier frequencies and proportions of potential patients by detecting causative gene variants associated with autosomal recessive bone dysplasia using a whole-genome reference panel of Japanese individuals
por: Nagaoka, Shinichi, et al.
Publicado: (2021)

Oral Microbiome Analysis in Prospective Genome Cohort Studies of the Tohoku Medical Megabank Project
por: Saito, Sakae, et al.
Publicado: (2021)

dbTMM: an integrated database of large-scale cohort, genome and clinical data for the Tohoku Medical Megabank Project
por: Ogishima, Soichi, et al.
Publicado: (2021)

Establishment of the early prediction models of low-birth-weight reveals influential genetic and environmental factors: a prospective cohort study
por: Mizuno, Satoshi, et al.
Publicado: (2023)

Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator
por: Yamada, Mitsuhiro, et al.
Publicado: (2021)

Security controls in an integrated Biobank to protect privacy in data sharing: rationale and study design
por: Takai-Igarashi, Takako, et al.
Publicado: (2017)

Plasma metabolic disturbances during pregnancy and postpartum in women with depression
por: Yu, Zhiqian, et al.
Publicado: (2022)

ALCOdb: Gene Coexpression Database for Microalgae
por: Aoki, Yuichi, et al.
Publicado: (2016)

Trío /
por: Garibay, Ricardo
Publicado: (1993)

The trio
Publicado: (1997)

Pathological variants in genes associated with disorders of sex development and central causes of hypogonadism in a whole-genome reference panel of 8380 Japanese individuals
por: Shiga, Naomi, et al.
Publicado: (2022)

Nrf2 plays a critical role in the metabolic response during and after spaceflight
por: Uruno, Akira, et al.
Publicado: (2021)

Trio. Remenbranzas
por: Dorantes, Edgar

Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals
por: Nagasaki, Masao, et al.
Publicado: (2015)

Clair3-trio: high-performance Nanopore long-read variant calling in family trios with trio-to-trio deep neural networks
por: Su, Junhao, et al.
Publicado: (2022)

Guitar trios Trios concertants, op. 18 /
por: Fossa, François de, 1775-1849
Publicado: (1994)

Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers
por: Okazaki, Keito, et al.
Publicado: (2020)

Publisher Correction: Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers
por: Okazaki, Keito, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_u7kmfo68i8ufpu2q1d4nmnk9vv