Cargando…

DefectTrack: a deep learning-based multi-object tracking algorithm for quantitative defect analysis of in-situ TEM videos in real-time

In-situ irradiation transmission electron microscopy (TEM) offers unique insights into the millisecond-timescale post-cascade process, such as the lifetime and thermal stability of defect clusters, vital to the mechanistic understanding of irradiation damage in nuclear materials. Converting in-situ...

Descripción completa

Detalles Bibliográficos
Autores principales: Sainju, Rajat, Chen, Wei-Ying, Schaefer, Samuel, Yang, Qian, Ding, Caiwen, Li, Meimei, Zhu, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489724/
https://www.ncbi.nlm.nih.gov/pubmed/36127375
http://dx.doi.org/10.1038/s41598-022-19697-1
_version_ 1784792931533586432
author Sainju, Rajat
Chen, Wei-Ying
Schaefer, Samuel
Yang, Qian
Ding, Caiwen
Li, Meimei
Zhu, Yuanyuan
author_facet Sainju, Rajat
Chen, Wei-Ying
Schaefer, Samuel
Yang, Qian
Ding, Caiwen
Li, Meimei
Zhu, Yuanyuan
author_sort Sainju, Rajat
collection PubMed
description In-situ irradiation transmission electron microscopy (TEM) offers unique insights into the millisecond-timescale post-cascade process, such as the lifetime and thermal stability of defect clusters, vital to the mechanistic understanding of irradiation damage in nuclear materials. Converting in-situ irradiation TEM video data into meaningful information on defect cluster dynamic properties (e.g., lifetime) has become the major technical bottleneck. Here, we present a solution called the DefectTrack, the first dedicated deep learning-based one-shot multi-object tracking (MOT) model capable of tracking cascade-induced defect clusters in in-situ TEM videos in real-time. DefectTrack has achieved a Multi-Object Tracking Accuracy (MOTA) of 66.43% and a Mostly Tracked (MT) of 67.81% on the test set, which are comparable to state-of-the-art MOT algorithms. We discuss the MOT framework, model selection, training, and evaluation strategies for in-situ TEM applications. Further, we compare the DefectTrack with four human experts in quantifying defect cluster lifetime distributions using statistical tests and discuss the relationship between the material science domain metrics and MOT metrics. Our statistical evaluations on the defect lifetime distribution suggest that the DefectTrack outperforms human experts in accuracy and speed.
format Online
Article
Text
id pubmed-9489724
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-94897242022-09-22 DefectTrack: a deep learning-based multi-object tracking algorithm for quantitative defect analysis of in-situ TEM videos in real-time Sainju, Rajat Chen, Wei-Ying Schaefer, Samuel Yang, Qian Ding, Caiwen Li, Meimei Zhu, Yuanyuan Sci Rep Article In-situ irradiation transmission electron microscopy (TEM) offers unique insights into the millisecond-timescale post-cascade process, such as the lifetime and thermal stability of defect clusters, vital to the mechanistic understanding of irradiation damage in nuclear materials. Converting in-situ irradiation TEM video data into meaningful information on defect cluster dynamic properties (e.g., lifetime) has become the major technical bottleneck. Here, we present a solution called the DefectTrack, the first dedicated deep learning-based one-shot multi-object tracking (MOT) model capable of tracking cascade-induced defect clusters in in-situ TEM videos in real-time. DefectTrack has achieved a Multi-Object Tracking Accuracy (MOTA) of 66.43% and a Mostly Tracked (MT) of 67.81% on the test set, which are comparable to state-of-the-art MOT algorithms. We discuss the MOT framework, model selection, training, and evaluation strategies for in-situ TEM applications. Further, we compare the DefectTrack with four human experts in quantifying defect cluster lifetime distributions using statistical tests and discuss the relationship between the material science domain metrics and MOT metrics. Our statistical evaluations on the defect lifetime distribution suggest that the DefectTrack outperforms human experts in accuracy and speed. Nature Publishing Group UK 2022-09-20 /pmc/articles/PMC9489724/ /pubmed/36127375 http://dx.doi.org/10.1038/s41598-022-19697-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Sainju, Rajat
Chen, Wei-Ying
Schaefer, Samuel
Yang, Qian
Ding, Caiwen
Li, Meimei
Zhu, Yuanyuan
DefectTrack: a deep learning-based multi-object tracking algorithm for quantitative defect analysis of in-situ TEM videos in real-time
title DefectTrack: a deep learning-based multi-object tracking algorithm for quantitative defect analysis of in-situ TEM videos in real-time
title_full DefectTrack: a deep learning-based multi-object tracking algorithm for quantitative defect analysis of in-situ TEM videos in real-time
title_fullStr DefectTrack: a deep learning-based multi-object tracking algorithm for quantitative defect analysis of in-situ TEM videos in real-time
title_full_unstemmed DefectTrack: a deep learning-based multi-object tracking algorithm for quantitative defect analysis of in-situ TEM videos in real-time
title_short DefectTrack: a deep learning-based multi-object tracking algorithm for quantitative defect analysis of in-situ TEM videos in real-time
title_sort defecttrack: a deep learning-based multi-object tracking algorithm for quantitative defect analysis of in-situ tem videos in real-time
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489724/
https://www.ncbi.nlm.nih.gov/pubmed/36127375
http://dx.doi.org/10.1038/s41598-022-19697-1
work_keys_str_mv AT sainjurajat defecttrackadeeplearningbasedmultiobjecttrackingalgorithmforquantitativedefectanalysisofinsitutemvideosinrealtime
AT chenweiying defecttrackadeeplearningbasedmultiobjecttrackingalgorithmforquantitativedefectanalysisofinsitutemvideosinrealtime
AT schaefersamuel defecttrackadeeplearningbasedmultiobjecttrackingalgorithmforquantitativedefectanalysisofinsitutemvideosinrealtime
AT yangqian defecttrackadeeplearningbasedmultiobjecttrackingalgorithmforquantitativedefectanalysisofinsitutemvideosinrealtime
AT dingcaiwen defecttrackadeeplearningbasedmultiobjecttrackingalgorithmforquantitativedefectanalysisofinsitutemvideosinrealtime
AT limeimei defecttrackadeeplearningbasedmultiobjecttrackingalgorithmforquantitativedefectanalysisofinsitutemvideosinrealtime
AT zhuyuanyuan defecttrackadeeplearningbasedmultiobjecttrackingalgorithmforquantitativedefectanalysisofinsitutemvideosinrealtime