Deciphering multi-way interactions in the human genome

Chromatin architecture, a key regulator of gene expression, can be inferred using chromatin contact data from chromosome conformation capture, or Hi-C. However, classical Hi-C does not preserve multi-way contacts. Here we use long sequencing reads to map genome-wide multi-way contacts and investigat...

Descripción completa

Detalles Bibliográficos
Autores principales: Dotson, Gabrielle A., Chen, Can, Lindsly, Stephen, Cicalo, Anthony, Dilworth, Sam, Ryan, Charles, Jeyarajan, Sivakumar, Meixner, Walter, Stansbury, Cooper, Pickard, Joshua, Beckloff, Nicholas, Surana, Amit, Wicha, Max, Muir, Lindsey A., Rajapakse, Indika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489732/
https://www.ncbi.nlm.nih.gov/pubmed/36127324
http://dx.doi.org/10.1038/s41467-022-32980-z

Ejemplares similares

Ejemplares similares