Cargando…

Silencing circFTO inhibits malignant phenotype through modulating DUSP4 expression in clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is the most diagnosed malignancy in kidney. Studies on the role of circular RNAs in kidney cancer are increasing. In this study, we employed high throughput sequencing and tissue micro array to detect and verify one of the key circular RNAs, circFTO, in ccRCC....

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Chen, Zang, Yiwen, Wu, Siqi, Zhou, Quan, Ou, Yuxi, Ding, Qiang, Wang, Hao, Xiong, Zuquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489864/ https://www.ncbi.nlm.nih.gov/pubmed/36127345 http://dx.doi.org/10.1038/s41420-022-01138-7

Ejemplares similares

Correction: Silencing circFTO inhibits malignant phenotype through modulating DUSP4 expression in clear cell renal cell carcinoma
por: Yang, Chen, et al.
Publicado: (2022)

circFTO upregulates transforming growth factor-alpha through sponging miR-148a-3p to regulate high glucose-induced ARPE-19 cells injury
por: Huang, Yan, et al.
Publicado: (2022)

Circular Ribonucleic Acid circFTO Promotes Angiogenesis and Impairs Blood–Retinal Barrier Via Targeting the miR-128-3p/Thioredoxin Interacting Protein Axis in Diabetic Retinopathy
por: Guo, Jianjin, et al.
Publicado: (2021)

Circ-AFAP1 promote clear cell renal cell carcinoma growth and angiogenesis by the Circ-AFAP1/miR-374b-3p/VEGFA signaling axis
por: Ou, Yuxi, et al.
Publicado: (2022)

Loss of DUSP4 Expression as a Prognostic Biomarker in Clear Cell Renal Cell Carcinoma
por: Bang, Seongsik, et al.
Publicado: (2021)

N6‐methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO‐PGC‐1α signalling axis
por: Zhuang, Changshui, et al.
Publicado: (2019)

DUSP5 and DUSP6 modulate corneal epithelial cell proliferation
por: Wang, Zheng, et al.
Publicado: (2010)

CircDHRS3 inhibits prostate cancer cell proliferation and metastasis through the circDHRS3/miR-421/MEIS2 axis
por: Dai, Xiyu, et al.
Publicado: (2023)

DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway
por: Luo, Jing, et al.
Publicado: (2020)

Overexpression of steroid sulfotransferase genes is associated with worsened prognosis and with immune exclusion in clear cell-renal cell carcinoma
por: Li, Yuqing, et al.
Publicado: (2019)

Long non-coding RNA HOXA11-AS promotes the proliferation HCC cells by epigenetically silencing DUSP5
por: Liu, Bin, et al.
Publicado: (2017)

The cytotoxic action of BCI is not dependent on its stated DUSP1 or DUSP6 targets in neuroblastoma cells
por: Thompson, Elliott M., et al.
Publicado: (2022)

SKA1 promotes tumor metastasis via SAFB-mediated transcription repression of DUSP6 in clear cell renal cell carcinoma
por: Pu, Yan, et al.
Publicado: (2022)

DUSP4 Silencing Enhances the Sensitivity of Breast Cancer Cells to Doxorubicin through the Activation of the JNK/c-Jun Signalling Pathway
por: Al-Mutairi, Mashael S., et al.
Publicado: (2022)

CircDUSP16 promotes the tumorigenesis and invasion of gastric cancer by sponging miR-145-5p
por: Zhang, Zizhen, et al.
Publicado: (2019)

Silencing ARAF Suppresses the Malignant Phenotypes of Gallbladder Cancer Cells
por: Lin, Weiguo, et al.
Publicado: (2020)

Genetic Variants of HNF4A, WFS1, DUSP9, FTO, and ZFAND6 Genes Are Associated with Prediabetes Susceptibility and Inflammatory Markers in the Saudi Arabian Population
por: Binjawhar, Dalal N., et al.
Publicado: (2023)

FGF18 Inhibits Clear Cell Renal Cell Carcinoma Proliferation and Invasion via Regulating Epithelial-Mesenchymal Transition
por: Yang, Chen, et al.
Publicado: (2020)

Long noncoding RNA CRNDE promotes colorectal cancer cell proliferation via epigenetically silencing DUSP5/CDKN1A expression
por: Ding, Jie, et al.
Publicado: (2017)

FTO-mediated autophagy promotes progression of clear cell renal cell carcinoma via regulating SIK2 mRNA stability
por: Xu, Yawei, et al.
Publicado: (2022)

DUSPs, to MAP kinases and beyond
por: Huang, Ching-Yu, et al.
Publicado: (2012)

circRNA_0001679/miR-338-3p/DUSP16 axis aggravates acute lung injury
por: Zhu, Jiang, et al.
Publicado: (2022)

DUSP1 is involved in the progression of small cell carcinoma of the prostate
por: Zhang, Yajing, et al.
Publicado: (2018)

Malignant Clear Cell Hidradenoma of the Breast
por: Chambers, Isaac, et al.
Publicado: (2017)

Decreased DUSP26 Expression Promotes Malignant Behavior in Glioblastoma Cells via Deregulation of MAPK and Akt Signaling Pathway
por: Chen, Jiajia, et al.
Publicado: (2021)

DNA Methylation Profiling Revealed Promoter Hypermethylation-induced Silencing of p16, DDAH2 and DUSP1 in Primary Oral Squamous Cell Carcinoma
por: Khor, Goot Heah, et al.
Publicado: (2013)

FTO promotes clear cell renal cell carcinoma progression via upregulation of PDK1 through an m(6)A dependent pathway
por: Shen, Haixiang, et al.
Publicado: (2022)

BCI, an inhibitor of the DUSP1 and DUSP6 dual specificity phosphatases, enhances P2X7 receptor expression in neuroblastoma cells
por: Benito-León, María, et al.
Publicado: (2022)

circCIMT Silencing Promotes Cadmium‐Induced Malignant Transformation of Lung Epithelial Cells Through the DNA Base Excision Repair Pathway
por: Li, Meizhen, et al.
Publicado: (2023)

The preclinical assessment of XL388, a mTOR kinase inhibitor, as a promising anti-renal cell carcinoma agent
por: Xiong, Zuquan, et al.
Publicado: (2017)

Roles of N6‐Methyladenosine Demethylase FTO in Malignant Tumors Progression
por: Zheng, Qing-Kang, et al.
Publicado: (2021)

FTO mediated ERBB2 demethylation promotes tumor progression in esophageal squamous cell carcinoma cells
por: Zhao, Fangfang, et al.
Publicado: (2022)

Corrigendum: Decreased DUSP26 Expression Promotes Malignant Behavior in Glioblastoma Cells via Deregulation of MAPK and Akt Signaling Pathway
por: Chen, Jiajia, et al.
Publicado: (2021)

Autocrine DUSP28 signaling mediates pancreatic cancer malignancy via regulation of PDGF-A
por: Lee, Jungwhoi, et al.
Publicado: (2017)

RNA Sequencing Reveals Upregulation of RUNX1-RUNX1T1 Gene Signatures in Clear Cell Renal Cell Carcinoma
por: Xiong, Zuquan, et al.
Publicado: (2014)

Le silence de la for{circ}et : roman /
por: Goyémidé, Etienne
Publicado: (1984)

miR-122-5p suppresses the oncogenesis of PTC by inhibiting DUSP4 expression
por: Hu, Ning, et al.
Publicado: (2021)

CircMAPK9 promotes adipogenesis through modulating hsa-miR-1322/FTO axis in obesity
por: Chen, Shuai, et al.
Publicado: (2023)

Circ-ABCB10 Contributes to Paclitaxel Resistance in Breast Cancer Through Let-7a-5p/DUSP7 Axis
por: Yang, Weiping, et al.
Publicado: (2020)

Circ_0051079 silencing inhibits the malignant phenotypes of osteosarcoma cells by the TRIM66/Wnt/β-catenin pathway in a miR-625-5p-dependent manner
por: Wang, Weilin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_att283qkufb42cnq6oeuth9fom