From bench to bedside: The mGluR5 system in people with and without Autism Spectrum Disorder and animal model systems

The metabotropic glutamate receptor 5 (mGluR5) is a key regulator of excitatory (E) glutamate and inhibitory (I) γ-amino butyric acid (GABA) signalling in the brain. Despite the close functional ties between mGluR5 and E/I signalling, no-one has directly examined the relationship between mGluR5 and...

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Detalles Bibliográficos
Autores principales: Carey, Cornelia, Singh, Nisha, Dunn, Joel T., Sementa, Teresa, Mendez, Maria Andreina, Velthuis, Hester, Pereira, Andreia C., Pretzsch, Charlotte Marie, Horder, Jamie, Hader, Stefan, Lythgoe, David J., Rotaru, Diana-Georgina, Gee, Anthony, Cash, Diana, Veronese, Mattia, Murphy, Declan, McAlonan, Grainne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489881/
https://www.ncbi.nlm.nih.gov/pubmed/36127322
http://dx.doi.org/10.1038/s41398-022-02143-1

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