Case report: Myocarditis following COVID-19 protein subunit vaccination

We report findings in a 34-year-old female patient who presented with fulminant myocarditis 8 days after receiving the first dose of the ZF2001 RBD-subunit vaccine against coronavirus disease 2019 (COVID-19). Autopsy showed severe interstitial myocarditis, including multiple patchy infiltrations of...

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Detalles Bibliográficos
Autores principales: Dong, Yi-ming, Liu, Xia, Yang, Chen-teng, Qi, Qian, Shi, Wei-bo, Li, Ying-min, Zuo, Min, Wang, Song-jun, Bi, Hai-tao, Ma, Ru-fei, Zhang, Guo-zhong, Cong, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489902/
https://www.ncbi.nlm.nih.gov/pubmed/36158819
http://dx.doi.org/10.3389/fcvm.2022.970045
Descripción
Sumario:We report findings in a 34-year-old female patient who presented with fulminant myocarditis 8 days after receiving the first dose of the ZF2001 RBD-subunit vaccine against coronavirus disease 2019 (COVID-19). Autopsy showed severe interstitial myocarditis, including multiple patchy infiltrations of lymphocytes and monocytes in the myocardium of the left and right ventricular walls associated with myocyte degeneration and necrosis. This report highlights the details of clinical presentations and autopsy findings of myocarditis after ZF2001 (RBD-subunit vaccine) vaccination. The correlation between vaccination and death due to myocarditis is discussed.

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