Case report: Myocarditis following COVID-19 protein subunit vaccination

We report findings in a 34-year-old female patient who presented with fulminant myocarditis 8 days after receiving the first dose of the ZF2001 RBD-subunit vaccine against coronavirus disease 2019 (COVID-19). Autopsy showed severe interstitial myocarditis, including multiple patchy infiltrations of...

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Autores principales: Dong, Yi-ming, Liu, Xia, Yang, Chen-teng, Qi, Qian, Shi, Wei-bo, Li, Ying-min, Zuo, Min, Wang, Song-jun, Bi, Hai-tao, Ma, Ru-fei, Zhang, Guo-zhong, Cong, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489902/
https://www.ncbi.nlm.nih.gov/pubmed/36158819
http://dx.doi.org/10.3389/fcvm.2022.970045
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author Dong, Yi-ming
Liu, Xia
Yang, Chen-teng
Qi, Qian
Shi, Wei-bo
Li, Ying-min
Zuo, Min
Wang, Song-jun
Bi, Hai-tao
Ma, Ru-fei
Zhang, Guo-zhong
Cong, Bin
author_facet Dong, Yi-ming
Liu, Xia
Yang, Chen-teng
Qi, Qian
Shi, Wei-bo
Li, Ying-min
Zuo, Min
Wang, Song-jun
Bi, Hai-tao
Ma, Ru-fei
Zhang, Guo-zhong
Cong, Bin
author_sort Dong, Yi-ming
collection PubMed
description We report findings in a 34-year-old female patient who presented with fulminant myocarditis 8 days after receiving the first dose of the ZF2001 RBD-subunit vaccine against coronavirus disease 2019 (COVID-19). Autopsy showed severe interstitial myocarditis, including multiple patchy infiltrations of lymphocytes and monocytes in the myocardium of the left and right ventricular walls associated with myocyte degeneration and necrosis. This report highlights the details of clinical presentations and autopsy findings of myocarditis after ZF2001 (RBD-subunit vaccine) vaccination. The correlation between vaccination and death due to myocarditis is discussed.
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spelling pubmed-94899022022-09-22 Case report: Myocarditis following COVID-19 protein subunit vaccination Dong, Yi-ming Liu, Xia Yang, Chen-teng Qi, Qian Shi, Wei-bo Li, Ying-min Zuo, Min Wang, Song-jun Bi, Hai-tao Ma, Ru-fei Zhang, Guo-zhong Cong, Bin Front Cardiovasc Med Cardiovascular Medicine We report findings in a 34-year-old female patient who presented with fulminant myocarditis 8 days after receiving the first dose of the ZF2001 RBD-subunit vaccine against coronavirus disease 2019 (COVID-19). Autopsy showed severe interstitial myocarditis, including multiple patchy infiltrations of lymphocytes and monocytes in the myocardium of the left and right ventricular walls associated with myocyte degeneration and necrosis. This report highlights the details of clinical presentations and autopsy findings of myocarditis after ZF2001 (RBD-subunit vaccine) vaccination. The correlation between vaccination and death due to myocarditis is discussed. Frontiers Media S.A. 2022-09-07 /pmc/articles/PMC9489902/ /pubmed/36158819 http://dx.doi.org/10.3389/fcvm.2022.970045 Text en Copyright © 2022 Dong, Liu, Yang, Qi, Shi, Li, Zuo, Wang, Bi, Ma, Zhang and Cong. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Dong, Yi-ming
Liu, Xia
Yang, Chen-teng
Qi, Qian
Shi, Wei-bo
Li, Ying-min
Zuo, Min
Wang, Song-jun
Bi, Hai-tao
Ma, Ru-fei
Zhang, Guo-zhong
Cong, Bin
Case report: Myocarditis following COVID-19 protein subunit vaccination
title Case report: Myocarditis following COVID-19 protein subunit vaccination
title_full Case report: Myocarditis following COVID-19 protein subunit vaccination
title_fullStr Case report: Myocarditis following COVID-19 protein subunit vaccination
title_full_unstemmed Case report: Myocarditis following COVID-19 protein subunit vaccination
title_short Case report: Myocarditis following COVID-19 protein subunit vaccination
title_sort case report: myocarditis following covid-19 protein subunit vaccination
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489902/
https://www.ncbi.nlm.nih.gov/pubmed/36158819
http://dx.doi.org/10.3389/fcvm.2022.970045
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