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Expansion of the Inguinal Adipose Tissue Depot Correlates With Systemic Insulin Resistance in C57BL/6J Mice

To accommodate surplus energy, the adipose tissue expands by increasing adipocyte size (hypertrophy) and number (hyperplasia). The presence of hypertrophic adipocytes is a key characteristic of adipose tissue dysfunction. High-fat diet (HFD) fed C57BL/6J mice are a commonly used model to study obesi...

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Detalles Bibliográficos
Autores principales: Fryklund, Claes, Neuhaus, Mathis, Morén, Björn, Borreguero-Muñoz, Andrea, Lundmark, Richard, Stenkula, Karin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489915/
https://www.ncbi.nlm.nih.gov/pubmed/36158197
http://dx.doi.org/10.3389/fcell.2022.942374