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Effect of intravenous almitrine on intubation or mortality in patients with COVID-19 acute hypoxemic respiratory failure: A multicentre, randomised, double-blind, placebo-controlled trial

BACKGROUND: Severe hypoxemia in patients with COVID-19 pneumonia might result from hypoxic pulmonary vasoconstriction, contributing to ventilation/perfusion (V/Q) mismatch. Because almitrine improves V/Q, it might reduce the risk for mechanical ventilation (MV) in such patients. Our primary objectiv...

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Detalles Bibliográficos
Autores principales:	Kalfon, Pierre, Payen, Jean-François, Rousseau, Alexandra, Chousterman, Benjamin, Cachanado, Marine, Tibi, Annick, Audibert, Juliette, Depret, François, Constantin, Jean-Michel, Weiss, Emmanuel, Remerand, Francis, Freund, Yonathan, Simon, Tabassome, Riou, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489996/ https://www.ncbi.nlm.nih.gov/pubmed/36157895 http://dx.doi.org/10.1016/j.eclinm.2022.101663

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