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Hepatic Leptin Signaling Improves Hyperglycemia by Stimulating MAPK Phosphatase-3 Protein Degradation via STAT3

BACKGROUND & AIMS: Obesity-related hyperglycemia, with hepatic insulin resistance, has become an epidemic disease. Central neural leptin signaling was reported to improve hyperglycemia. The aim of this study was to investigate the effect of hepatic leptin signaling on controlling hyperglycemia....

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Detalles Bibliográficos
Autores principales: Huang, Xiaohua, He, Qin, Zhu, Heng, Fang, Zhengfeng, Che, Lianqiang, Lin, Yan, Xu, Shengyu, Zhuo, Yong, Hua, Lun, Wang, Jianping, Zou, Yuanfeng, Huang, Chao, Li, Lixia, Xu, Haiyan, Wu, De, Feng, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490031/
https://www.ncbi.nlm.nih.gov/pubmed/35863745
http://dx.doi.org/10.1016/j.jcmgh.2022.07.010