Mechanistic insight into the RNA-stimulated ATPase activity of tick-borne encephalitis virus helicase

The helicase domain of nonstructural protein 3 (NS3H) unwinds the double-stranded RNA replication intermediate in an ATP-dependent manner during the flavivirus life cycle. While the ATP hydrolysis mechanism of Dengue and Zika viruses NS3H has been extensively studied, little is known in the case of...

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Detalles Bibliográficos
Autores principales: Anindita, Paulina Duhita, Halbeisen, Marco, Řeha, David, Tuma, Roman, Franta, Zdenek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490040/
https://www.ncbi.nlm.nih.gov/pubmed/35987382
http://dx.doi.org/10.1016/j.jbc.2022.102383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490040/
https://www.ncbi.nlm.nih.gov/pubmed/35987382
http://dx.doi.org/10.1016/j.jbc.2022.102383

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