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Mechanistic insight into the RNA-stimulated ATPase activity of tick-borne encephalitis virus helicase
The helicase domain of nonstructural protein 3 (NS3H) unwinds the double-stranded RNA replication intermediate in an ATP-dependent manner during the flavivirus life cycle. While the ATP hydrolysis mechanism of Dengue and Zika viruses NS3H has been extensively studied, little is known in the case of...
Autores principales: | Anindita, Paulina Duhita, Halbeisen, Marco, Řeha, David, Tuma, Roman, Franta, Zdenek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490040/ https://www.ncbi.nlm.nih.gov/pubmed/35987382 http://dx.doi.org/10.1016/j.jbc.2022.102383 |
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