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Review of various NAMPT inhibitors for the treatment of cancer

Nicotinamide phosphoribosyltransferase (NAMPT) is a rate-limiting enzyme in the NAD salvage pathway of mammalian cells and is overexpressed in numerous types of cancers. These include breast cancer, ovarian cancer, prostate cancer, gastric cancer, colorectal cancer, glioma, and b-cell lymphoma. NAMP...

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Detalles Bibliográficos
Autores principales:	Wei, Yichen, Xiang, Haotian, Zhang, Wenqiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490061/ https://www.ncbi.nlm.nih.gov/pubmed/36160449 http://dx.doi.org/10.3389/fphar.2022.970553

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