Hepatocyte-Secreted Autotaxin Exacerbates Nonalcoholic Fatty Liver Disease Through Autocrine Inhibition of the PPARα/FGF21 Axis

BACKGROUND & AIMS: The prevalence of nonalcoholic fatty liver disease (NAFLD) has reached epidemic proportions globally as a result of the rapid increase in obesity. However, there is no Food and Drug Administration–approved pharmacotherapy available for NAFLD. This study investigated the role o...

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Detalles Bibliográficos
Autores principales: Qiu, Han, Song, Erfei, Hu, Yue, Li, Tengfei, Ku, Kam Ching, Wang, Cunchuan, Cheung, Bernard M.Y., Cheong, Lai Yee, Wang, Qin, Wu, Xiaoping, Hoo, Ruby L.C., Wang, Yong, Xu, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490100/
https://www.ncbi.nlm.nih.gov/pubmed/35931383
http://dx.doi.org/10.1016/j.jcmgh.2022.07.012

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