The role of aging in cancer

Many cancers show an increase in incidence with age, and age is the biggest single risk factor for many cancers. However, the molecular basis of this relationship is poorly understood. Through a collection of review articles, our thematic issue discusses the link between aging and cancer in aspects...

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Detalles Bibliográficos
Autores principales: Havas, Aaron, Yin, Shanshan, Adams, P. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490134/
https://www.ncbi.nlm.nih.gov/pubmed/36128609
http://dx.doi.org/10.1002/1878-0261.13302
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author Havas, Aaron
Yin, Shanshan
Adams, P. D.
author_facet Havas, Aaron
Yin, Shanshan
Adams, P. D.
author_sort Havas, Aaron
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description Many cancers show an increase in incidence with age, and age is the biggest single risk factor for many cancers. However, the molecular basis of this relationship is poorly understood. Through a collection of review articles, our thematic issue discusses the link between aging and cancer in aspects including somatic mutations, proteostasis, mitochondria, metabolism, senescence, epigenetic regulation, immune regulation, DNA damage, and telomere function.[Image: see text]
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spelling pubmed-94901342022-09-30 The role of aging in cancer Havas, Aaron Yin, Shanshan Adams, P. D. Mol Oncol Editorial Many cancers show an increase in incidence with age, and age is the biggest single risk factor for many cancers. However, the molecular basis of this relationship is poorly understood. Through a collection of review articles, our thematic issue discusses the link between aging and cancer in aspects including somatic mutations, proteostasis, mitochondria, metabolism, senescence, epigenetic regulation, immune regulation, DNA damage, and telomere function.[Image: see text] John Wiley and Sons Inc. 2022-09-20 2022-09 /pmc/articles/PMC9490134/ /pubmed/36128609 http://dx.doi.org/10.1002/1878-0261.13302 Text en © 2022 The Authors. Molecular Oncology published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Editorial
Havas, Aaron
Yin, Shanshan
Adams, P. D.
The role of aging in cancer
title The role of aging in cancer
title_full The role of aging in cancer
title_fullStr The role of aging in cancer
title_full_unstemmed The role of aging in cancer
title_short The role of aging in cancer
title_sort role of aging in cancer
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490134/
https://www.ncbi.nlm.nih.gov/pubmed/36128609
http://dx.doi.org/10.1002/1878-0261.13302
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