Differential effects of ketoconazole, fluconazole, and itraconazole on the pharmacokinetics of pyrotinib in vitro and in vivo

It has been reported that drug-drug interactions (DDIs) can affect the pharmacokinetics and pharmacodynamics of various oral drugs. To better understand the effects of azole antifungal drugs (ketoconazole, fluconazole, and itraconazole) on pyrotinib’s pharmacokinetics, DDIs between pyrotinib and thr...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Li, Wu, Fan, Xu, Jia, Wang, Yu, Fei, Weidong, Jiang, Hui, Geng, Peiwu, Zhou, Quan, Wang, Shuanghu, Zheng, Yongquan, Deng, Huadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490176/
https://www.ncbi.nlm.nih.gov/pubmed/36160438
http://dx.doi.org/10.3389/fphar.2022.962731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490176/
https://www.ncbi.nlm.nih.gov/pubmed/36160438
http://dx.doi.org/10.3389/fphar.2022.962731

Ejemplares similares