Cargando…

Differential effects of ketoconazole, fluconazole, and itraconazole on the pharmacokinetics of pyrotinib in vitro and in vivo

It has been reported that drug-drug interactions (DDIs) can affect the pharmacokinetics and pharmacodynamics of various oral drugs. To better understand the effects of azole antifungal drugs (ketoconazole, fluconazole, and itraconazole) on pyrotinib’s pharmacokinetics, DDIs between pyrotinib and thr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Li, Wu, Fan, Xu, Jia, Wang, Yu, Fei, Weidong, Jiang, Hui, Geng, Peiwu, Zhou, Quan, Wang, Shuanghu, Zheng, Yongquan, Deng, Huadong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490176/ https://www.ncbi.nlm.nih.gov/pubmed/36160438 http://dx.doi.org/10.3389/fphar.2022.962731

Ejemplares similares

Comparative Hepatotoxicity of Fluconazole, Ketoconazole, Itraconazole, Terbinafine, and Griseofulvin in Rats
por: Khoza, Star, et al.
Publicado: (2017)

Effects of bergapten on the pharmacokinetics of macitentan in rats both in vitro and in vivo
por: Xu, Jia, et al.
Publicado: (2023)

Inhibitory Effect of Imperatorin on the Pharmacokinetics of Diazepam In Vitro and In Vivo
por: Zhou, Yunfang, et al.
Publicado: (2020)

Inhibition and Induction by Poziotinib of Different Rat Cytochrome P450 Enzymes In Vivo and in an In Vitro Cocktail Method
por: Wang, Jinhui, et al.
Publicado: (2021)

Prediction of pyrotinib exposure based on physiologically-based pharmacokinetic model and endogenous biomarker
por: Zhang, Miao, et al.
Publicado: (2022)

Evaluation of commonly used cardiovascular drugs in inhibiting vonoprazan metabolism in vitro and in vivo
por: Wang, Yiran, et al.
Publicado: (2022)

In Vitro and In Vivo Rat Model Assessments of the Effects of Vonoprazan on the Pharmacokinetics of Venlafaxine
por: Chen, Feifei, et al.
Publicado: (2020)

Effects of avitinib on the pharmacokinetics of osimertinib in vitro and in vivo in rats
por: Wu, Qingjun, et al.
Publicado: (2020)

Effects of the CYP3A inhibitors, voriconazole, itraconazole, and fluconazole on the pharmacokinetics of osimertinib in rats
por: Lou, Yutao, et al.
Publicado: (2023)

Inhibitory effect of Schisandrin on the pharmacokinetics of poziotinib in vivo and in vitro by UPLC‐MS/MS
por: Wang, Shuanghu, et al.
Publicado: (2023)

Evaluation of the inhibitory effect of azoles on pharmacokinetics of lenvatinib in rats both in vivo and in vitro by UPLC‐MS/MS
por: Xia, Mengming, et al.
Publicado: (2023)

UPLC-MS/MS Measurement of the Effect of Isavuconazole, Itraconazole and Fluconazole on the Pharmacokinetics of Selinexor in Rats
por: Li, Shuang-long, et al.
Publicado: (2020)

Multiple Administrations of Itraconazole Increase Plasma Exposure to Pyrotinib in Chinese Healthy Adults
por: Liu, Yueyue, et al.
Publicado: (2021)

Effect of itraconazole and fluconazole on the pharmacokinetics of valemetostat: An open‐label, phase I study in healthy subjects
por: Tachibana, Masaya, et al.
Publicado: (2023)

Study on Formulation, in vivo Exposure, and Passive Targeting of Intravenous Itraconazole Nanosuspensions
por: Yuan, Qi, et al.
Publicado: (2019)

In Vitro Susceptibility of Malassezia pachydermatis Isolates from Canine Skin with Atopic Dermatitis to Ketoconazole and Itraconazole in East Asia
por: WATANABE, Shion, et al.
Publicado: (2013)

Cytochrome P450-Based Drug-Drug Interactions of Vonoprazan In Vitro and In Vivo
por: Wang, Yiran, et al.
Publicado: (2020)

Population Pharmacokinetics and Cerebrospinal Fluid Penetration of Fluconazole in Adults with Cryptococcal Meningitis
por: Stott, Katharine E., et al.
Publicado: (2018)

Tacrolimus Increases the Effectiveness of Itraconazole and Fluconazole against Sporothrix spp.
por: Borba-Santos, Luana P., et al.
Publicado: (2017)

Severe Adverse Reactions Following Ketoconazole, Fluconazole, and Environmental Exposures: A Case Report
por: Lieberman, Allan, et al.
Publicado: (2018)

Effects of dacomitinib on the pharmacokinetics of poziotinib in vivo and in vitro
por: Ji, Weiping, et al.
Publicado: (2021)

Antifungal prophylaxis with posaconazole vs. fluconazole or itraconazole in pediatric patients with neutropenia
por: Döring, M., et al.
Publicado: (2015)

Inhibitory Effect of Lygodium Root on the Cytochrome P450 3A Enzyme in vitro and in vivo
por: Zhou, Yunfang, et al.
Publicado: (2020)

Effects of Avitinib on CYP450 Enzyme Activity in vitro and in vivo in Rats
por: Shi, Yong, et al.
Publicado: (2021)

Effect of ketoconazole on the pharmacokinetics of axitinib in healthy volunteers
por: Pithavala, Yazdi K., et al.
Publicado: (2010)

Pharmacokinetic interaction of ketoconazole, clarithromycin, and midazolam with riociguat
por: Becker, Corina, et al.
Publicado: (2013)

Effects of Ketoconazole on the Pharmacokinetics of Ponatinib in Healthy Subjects
por: Narasimhan, Narayana I, et al.
Publicado: (2013)

Influence of Gender, Body Mass Index, and Age on the Pharmacokinetics of Itraconazole in Healthy Subjects: Non-Compartmental Versus Compartmental Analysis
por: Miljković, Milijana N., et al.
Publicado: (2022)

Antifungal Activity of Melaleuca alternifolia Essential Oil (TTO) and Its Synergy with Itraconazole or Ketoconazole against Trichophyton rubrum
por: Roana, Janira, et al.
Publicado: (2021)

Effects of Voriconazole on the Pharmacokinetics of Vonoprazan in Rats
por: Shen, Jiquan, et al.
Publicado: (2020)

Effects of Cytochrome P450 Inhibitors on Itraconazole and Fluconazole Induced Cytotoxicity in Hepatocytes
por: Somchit, Nhareet, et al.
Publicado: (2009)

Drug susceptibility in emerging fungal infections: tests with fluconazole, itraconazole, and amphotericin B
por: Fay, Vanessa da Silva, et al.
Publicado: (2018)

Itraconazole Improves Vulvodynia in Fungus Culture-Negative Patients Post Fluconazole Failure
por: Rothenberger, Rodger, et al.
Publicado: (2021)

Effects of Ketoconazole and Rifampicin on the Pharmacokinetics of Nintedanib in Healthy Subjects
por: Luedtke, Doreen, et al.
Publicado: (2018)

In Vitro and In Vivo Assessment of Metabolic Drug Interaction Potential of Dutasteride with Ketoconazole
por: Seo, Seong-Wook, et al.
Publicado: (2019)

Evaluation of fluconazole, itraconazole, and voriconazole activity on Candida albicans: A case control study
por: Partha, Agung Dewi Sekar Langit, et al.
Publicado: (2022)

Fluconazole as a Safe and Effective Alternative to Ketoconazole in Controlling Hypercortisolism of Recurrent Cushing’s Disease: A Case Report
por: Teng Chai, Shu, et al.
Publicado: (2018)

Application of an Accessible Interface for Pharmacokinetic Modeling and In Vitro to In Vivo Extrapolation
por: Hines, David E., et al.
Publicado: (2022)

Functional Nanocarriers for Delivering Itraconazole Against Fungal Intracellular Infections
por: Mejía, Susana P., et al.
Publicado: (2021)

Effects of Ketoconazole on the Pharmacokinetics of Lenvatinib (E7080) in Healthy Participants
por: Shumaker, Robert, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_dk9egpbqsicacfaaaavvcfhqb9