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Mn(3+)/Mn(4+) ion-doped carbon dots as fenton-like catalysts for fluorescence dual-signal detection of dopamine

Carbon dots (CDs), a new zero-dimensional material, have ignited a revolution in the fields of sensing, bioimaging, and biomedicine. However, the difficulty of preparing CDs with Fenton-like catalytic properties has seriously hindered their application in the diagnosis of oxidation/reduction biomole...

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Autores principales: Zhu, Peide, Zhao, Xuelin, Zhang, Yuqi, Liu, Yinping, Zhao, Ziyi, Yang, Ziji, Liu, Xinzhu, Zhang, Weiye, Guo, Zixuan, Wang, Xiao, Niu, Yingchun, Xu, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490222/
https://www.ncbi.nlm.nih.gov/pubmed/36159685
http://dx.doi.org/10.3389/fbioe.2022.964814
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author Zhu, Peide
Zhao, Xuelin
Zhang, Yuqi
Liu, Yinping
Zhao, Ziyi
Yang, Ziji
Liu, Xinzhu
Zhang, Weiye
Guo, Zixuan
Wang, Xiao
Niu, Yingchun
Xu, Meng
author_facet Zhu, Peide
Zhao, Xuelin
Zhang, Yuqi
Liu, Yinping
Zhao, Ziyi
Yang, Ziji
Liu, Xinzhu
Zhang, Weiye
Guo, Zixuan
Wang, Xiao
Niu, Yingchun
Xu, Meng
author_sort Zhu, Peide
collection PubMed
description Carbon dots (CDs), a new zero-dimensional material, have ignited a revolution in the fields of sensing, bioimaging, and biomedicine. However, the difficulty of preparing CDs with Fenton-like catalytic properties has seriously hindered their application in the diagnosis of oxidation/reduction biomolecules or metal ions. Here, an innovative method was successfully established to synthesize Mn(3+)/Mn(4+) ion-doped blue-green fluorescent CDs with Fenton-like catalytic properties using manganese acetate as the manganese source. Specifically, the CDs prepared here were equipped with functional groups of -COOH, NH(2), C=O, and Mn-O, offering the possibility to function as a fluorescence sensor. More importantly, the introduction of manganese acetate resulted in the preparation of CDs with Fenton-like catalytic properties, and the dual-signal fluorescence detection of dopamine (DA) was realized with linear ranges of 100–275 nM and 325–525 nM, and the detection limits were 3 and 12 nM, respectively. In addition, due to the Fenton-like catalytic activity of Mn(3+)/Mn(4+) ion-doped CDs, the material has broad application prospects in the detection of oxidation/reduction biomolecules or metal ions related to disease diagnosis and prevention.
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spelling pubmed-94902222022-09-22 Mn(3+)/Mn(4+) ion-doped carbon dots as fenton-like catalysts for fluorescence dual-signal detection of dopamine Zhu, Peide Zhao, Xuelin Zhang, Yuqi Liu, Yinping Zhao, Ziyi Yang, Ziji Liu, Xinzhu Zhang, Weiye Guo, Zixuan Wang, Xiao Niu, Yingchun Xu, Meng Front Bioeng Biotechnol Bioengineering and Biotechnology Carbon dots (CDs), a new zero-dimensional material, have ignited a revolution in the fields of sensing, bioimaging, and biomedicine. However, the difficulty of preparing CDs with Fenton-like catalytic properties has seriously hindered their application in the diagnosis of oxidation/reduction biomolecules or metal ions. Here, an innovative method was successfully established to synthesize Mn(3+)/Mn(4+) ion-doped blue-green fluorescent CDs with Fenton-like catalytic properties using manganese acetate as the manganese source. Specifically, the CDs prepared here were equipped with functional groups of -COOH, NH(2), C=O, and Mn-O, offering the possibility to function as a fluorescence sensor. More importantly, the introduction of manganese acetate resulted in the preparation of CDs with Fenton-like catalytic properties, and the dual-signal fluorescence detection of dopamine (DA) was realized with linear ranges of 100–275 nM and 325–525 nM, and the detection limits were 3 and 12 nM, respectively. In addition, due to the Fenton-like catalytic activity of Mn(3+)/Mn(4+) ion-doped CDs, the material has broad application prospects in the detection of oxidation/reduction biomolecules or metal ions related to disease diagnosis and prevention. Frontiers Media S.A. 2022-09-07 /pmc/articles/PMC9490222/ /pubmed/36159685 http://dx.doi.org/10.3389/fbioe.2022.964814 Text en Copyright © 2022 Zhu, Zhao, Zhang, Liu, Zhao, Yang, Liu, Zhang, Guo, Wang, Niu and Xu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Zhu, Peide
Zhao, Xuelin
Zhang, Yuqi
Liu, Yinping
Zhao, Ziyi
Yang, Ziji
Liu, Xinzhu
Zhang, Weiye
Guo, Zixuan
Wang, Xiao
Niu, Yingchun
Xu, Meng
Mn(3+)/Mn(4+) ion-doped carbon dots as fenton-like catalysts for fluorescence dual-signal detection of dopamine
title Mn(3+)/Mn(4+) ion-doped carbon dots as fenton-like catalysts for fluorescence dual-signal detection of dopamine
title_full Mn(3+)/Mn(4+) ion-doped carbon dots as fenton-like catalysts for fluorescence dual-signal detection of dopamine
title_fullStr Mn(3+)/Mn(4+) ion-doped carbon dots as fenton-like catalysts for fluorescence dual-signal detection of dopamine
title_full_unstemmed Mn(3+)/Mn(4+) ion-doped carbon dots as fenton-like catalysts for fluorescence dual-signal detection of dopamine
title_short Mn(3+)/Mn(4+) ion-doped carbon dots as fenton-like catalysts for fluorescence dual-signal detection of dopamine
title_sort mn(3+)/mn(4+) ion-doped carbon dots as fenton-like catalysts for fluorescence dual-signal detection of dopamine
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490222/
https://www.ncbi.nlm.nih.gov/pubmed/36159685
http://dx.doi.org/10.3389/fbioe.2022.964814
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